Morehouse School of Medicine?s overall strategic goal is to increase the critical mass of talented research faculty pursuing health disparities research;augment the pipeline of minority students/fellows pursuing research training in biomedical, clinical and behavioral sciences, and provide the infrastructure needed for investigators to achieve national recognition for their scientific discoveries and translation of new knowledge into community solutions and improved patient care for minorities. The goal of the 5-Year Endowment Strategic Plan is to support personalized prevention and intervention research through the translational continuum of basic science, clinical, and community-based research to move discoveries from the laboratory more rapidly into clinical applications and into widespread use in office settings and in the community. To this end, we will build capacity in Molecular Genetics Research, Clinical Research, and Community-based Prevention Research Infrastructure that will support the following objectives: I) Enhance the basic (and translational) research infrastructure for utilizing molecular (genomic, proteomic, and metabolomics) diagnostics and evidence-based, rationale design of therapies and technologies to reduce health disparities;II) Expand the critical mass of talented clinical investigators capable of accelerating translational science in the health disparity research focus areas related to: cancer, neuroscience/stroke, women?s health and cardio-metabolic disorders; III) Conduct community-based and public health informatics research to further define and understand the epidemiology of racial and ethnic health disparities and to develop innovative approaches to addressing cancer, neuroscience/stroke and cardiovascular disparities at the population level;and IV) Build a perpetual resource that will enable MSM to continually support growth and development in the areas of cancer, women?s health, neuroscience/stroke and cardiovascular disorders.

Public Health Relevance

African Americans have the highest mortality rates from all major causes of death (cancer, diabetes, stroke, heart disease, AIDS). This project will seek to reduce these disparities by building research capacity for personalized clinical and community prevention strategies.

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Research and Institutional Resources Health Disparities Endowment Grants -Capacity Building (S21)
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Special Emphasis Panel (ZMD1)
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Stinson, Nathaniel
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Morehouse School of Medicine
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O'Bryant, Zaven; Leng, Tiandong; Liu, Mingli et al. (2016) Acid Sensing Ion Channels (ASICs) in NS20Y cells - potential role in neuronal differentiation. Mol Brain 9:68
Henry-Akintobi, Tabia; Laster, Nastassia; Trotter, Jennie et al. (2016) The Health, Enlightenment, Awareness, and Living (HEAL) Intervention: Outcome of an HIV and Hepatitis B and C Risk Reduction Intervention. Int J Environ Res Public Health 13:
Inoue, Koichi; Sakuma, Eisuke; Morimoto, Hiroyuki et al. (2016) Serum- and glucocorticoid-inducible kinases in microglia. Biochem Biophys Res Commun 478:53-9
Wu, Junjun; Leng, Tiandong; Jing, Lan et al. (2016) Two di-leucine motifs regulate trafficking and function of mouse ASIC2a. Mol Brain 9:9
Gianesini, Coralie; Hiragaki, Susumu; Laurent, Virginie et al. (2016) Cone Viability Is Affected by Disruption of Melatonin Receptors Signaling. Invest Ophthalmol Vis Sci 57:94-104
Mullen, McKay; Gonzalez-Perez, Ruben Rene (2016) Leptin-Induced JAK/STAT Signaling and Cancer Growth. Vaccines (Basel) 4:
Simmons, Lauren J; Surles-Zeigler, Monique C; Li, Yonggang et al. (2016) Regulation of inflammatory responses by neuregulin-1 in brain ischemia and microglial cells in vitro involves the NF-kappa B pathway. J Neuroinflammation 13:237
White, Todd E; Surles-Zeigler, Monique C; Ford, Gregory D et al. (2016) Bilateral gene interaction hierarchy analysis of the cell death gene response emphasizes the significance of cell cycle genes following unilateral traumatic brain injury. BMC Genomics 17:130
Vann, Kiara T; Xiong, Zhi-Gang (2016) Optogenetics for neurodegenerative diseases. Int J Physiol Pathophysiol Pharmacol 8:1-8
Zellner, Tiffany; Trotter, Jennie; Lenoir, Shelia et al. (2016) Color It Real: A Program to Increase Condom Use and Reduce Substance Abuse and Perceived Stress. Int J Environ Res Public Health 13:ijerph13010051

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