The Infectious Diseases Training Program is in its 34th year. The objective is to provide a rich interdisciplinary experience in infectious diseases research in order to prepare our trainees for careers as independent investigators. The cornerstone is the side-by-side education of predoctoral, M.D. and Ph.D. postdoctoral fellows. The rationale is that integration of clinical and basic science provides the varied perspectives and techniques required for creative research to combat infections. The design includes a an Executive Committee that selects predoctoral trainees from a pool of rising 2nd year graduate students, and selects postdoctoral applicants based on nominations from both mentors and the Infectious Diseases Division. Training is enriched by the monthly Research in Progress for trainees chaired by the Director, graduate courses taught by Program faculty, MS &MPH degrees in clinical investigation, seminars, research day, annual faculty retreat and journal clubs. Trainees are also taught the responsible conduct of research and are provided instruction in grant writing and laboratory and project management. The 27 faculty are 96% NIH supported (mean annual direct costs $852,000), interactive, senior (18/26 full Professors, although select """"""""up and coming"""""""" junior faculty are included), from 8 Departments, with 20 PhDs, 11 MDs, and 1 DVM. The average mentor trained 7 pre- and 9 postdocs in the last 10 years, 94% of whom remain in research. Evaluation of the Program includes an annual faculty retreat, trainee and graduate questionnaire and External Advisory Committee site visits. Institutional support includes funding of all 1st year predoctoral fellows, the seminar series, and construction of a new research building occupied last year by 53% (16/27) of mentors. NIH support is requested for 5 predoctoral, 5 M.D. and 2 Ph.D. postdoctoral fellows (no change from the prior funding period). The average matriculated predoctoral student in Infectious Diseases Program has GRE scores of 570/704/4.7 and a grade point average of 3.63. Admission is highly competitive, with only 31% (5/16) of rising 2nd year predoctoral trainees accepted by the Program in 2010 despite their expressed interest in infectious diseases and their excellent qualifications. Progress since the last funding period includes 100% retention of trainees in the Program, and a 24% increase in mentor extramural support. 97% of predoctoral and 90% of postdoctoral fellows graduates in the last 10 years remain in research. Peer-reviewed original publications average 3.5 for graduating fellows. Underrepresented minorities comprise 15% of postdoctoral fellows for both the last 5 and 10 years, and 28% (5/18) and 25% (5/20) of predoctoral fellows supported for the last 5 and 10 respectively (including for predocs individuals with disabilities and disadvantaged). For the 10 year period, 21% of trainees are under-represented minority, disabled or disadvantaged. Academic and research positions are held by 84% (21/25) of postdoctoral and 95% (19/20) of predoctoral graduates, and 7 K awards and 3 individual fellowships have been awarded.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI007046-37
Application #
8499176
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Robbins, Christiane M
Project Start
1977-07-01
Project End
2017-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
37
Fiscal Year
2013
Total Cost
$549,363
Indirect Cost
$35,074
Name
University of Virginia
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
065391526
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Anderson, Christopher J; Satkovich, John; Köseo?lu, Volkan K et al. (2018) The Ethanolamine Permease EutH Promotes Vacuole Adaptation of Salmonella enterica and Listeria monocytogenes during Macrophage Infection. Infect Immun 86:
Camelo, Felipe; Le, Anne (2018) The Intricate Metabolism of Pancreatic Cancers. Adv Exp Med Biol 1063:73-81
Knick, Terry; Sherbuk, Jacqueline E; Dillingham, Rebecca (2018) Knowledge of Hepatitis C Risk Factors is Lower in High Incidence Regions. J Community Health :
Jung, Jin G; Le, Anne (2018) Targeting Metabolic Cross Talk between Cancer Cells and Cancer-Associated Fibroblasts. Adv Exp Med Biol 1063:167-178
Nguyen, Tu; Le, Anne (2018) The Metabolism of Renal Cell Carcinomas and Liver Cancer. Adv Exp Med Biol 1063:107-118
Madden, Gregory R; Weinstein, Robert A; Sifri, Costi D (2018) Diagnostic Stewardship for Healthcare-Associated Infections: Opportunities and Challenges to Safely Reduce Test Use. Infect Control Hosp Epidemiol 39:214-218
Madden, Gregory R; Poulter, Melinda D; Sifri, Costi D (2018) Diagnostic stewardship and the 2017 update of the IDSA-SHEA Clinical Practice Guidelines for Clostridium difficile Infection. Diagnosis (Berl) 5:119-125
Madden, Gregory R; German Mesner, Ian; Cox, Heather L et al. (2018) Reduced Clostridium difficile Tests and Laboratory-Identified Events With a Computerized Clinical Decision Support Tool and Financial Incentive. Infect Control Hosp Epidemiol 39:737-740
Schnee, Amanda E; Haque, Rashidul; Taniuchi, Mami et al. (2018) Evaluation of Two New Membrane-Based and Microtiter Plate Enzyme-Linked Immunosorbent Assays for Detection of Campylobacter jejuni in Stools of Bangladeshi Children. J Clin Microbiol 56:
Quinones, Addison; Le, Anne (2018) The Multifaceted Metabolism of Glioblastoma. Adv Exp Med Biol 1063:59-72

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