There is a continuing and urgent need for greater understanding of virus infections and, consequently, a need for a robust virology research community in the U.S and the world. The purpose of the Virology Training Program at the University of Iowa is to train young scientists to be productive members of that research community. The Virology Training Grant at the University of Iowa helps in two ways. First, it fosters the rigorous training of PhD students in the study of virology. Second, it promotes interaction among students and faculty interested in virology across the University of Iowa. By providing stipend support and travel funds for graduate students, the Training Grant will facilitat recruitment of students interested in virology. By establishing curriculum requirements that include research and literature seminars for the virology community and the collaborative teaching of virology training courses the Training Grant will promote interaction in the larger virology community at the University of Iowa and beyond. There are ten Virology Training Grant faculty who represent a wide variety of research interests from study of very basic processes in the molecular and cellular biology of virus replication, to study of host animal responses to virus infection, to study of the most efficient mechanisms for gene delivery by viruses. We seek support for three predoctoral graduate students for two years between their second and fourth years of study.
Virus infections have critical public health relevance because: (i) They are a major cause of human disease. (ii) Their intimate relationship with host cells makes them useful tools for studying normal cellular functions. (iii) They are vehicles for gene delivery in remedial gene therapy and vaccine development. There is a need to train scientists who can meet the public health threat and exploit opportunities presented by viruses.
|Brouillette, Rachel B; Phillips, Elisabeth K; Patel, Radhika et al. (2018) TIM-1 Mediates Dystroglycan-Independent Entry of Lassa Virus. J Virol 92:|
|Balasubramaniam, Muthukumar; Zhou, Jing; Addai, Amma et al. (2018) PF74 Inhibits HIV-1 Integration by Altering The Composition of the Preintegration Complex. J Virol :|
|Welch, Jennifer L; Kaddour, Hussein; Schlievert, Patrick M et al. (2018) Semen exosomes promote transcriptional silencing of HIV-1 by disrupting NF-kB/Sp1/Tat circuitry. J Virol :|
|Grunewald, Matthew E; Fehr, Anthony R; Athmer, Jeremiah et al. (2018) The coronavirus nucleocapsid protein is ADP-ribosylated. Virology 517:62-68|
|Brouillette, Rachel B; Maury, Wendy (2017) Production of Filovirus Glycoprotein-Pseudotyped Vesicular Stomatitis Virus for Study of Filovirus Entry Mechanisms. Methods Mol Biol 1628:53-63|
|Vijay, Rahul; Fehr, Anthony R; Janowski, Ann M et al. (2017) Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling. Proc Natl Acad Sci U S A 114:E5444-E5453|
|Welch, Jennifer L; Madison, Marisa N; Margolick, Joseph B et al. (2017) Effect of prolonged freezing of semen on exosome recovery and biologic activity. Sci Rep 7:45034|
|Sinn, P L; Hwang, B-Y; Li, N et al. (2017) Novel GP64 envelope variants for improved delivery to human airway epithelial cells. Gene Ther 24:674-679|
|Wheeler, D Lori; Athmer, Jeremiah; Meyerholz, David K et al. (2017) Murine Olfactory Bulb Interneurons Survive Infection with a Neurotropic Coronavirus. J Virol :|
|Brouillette, Rachel B; Phillips, Elisabeth K; Ayithan, Natarajan et al. (2017) Differences in Glycoprotein Complex Receptor Binding Site Accessibility Prompt Poor Cross-Reactivity of Neutralizing Antibodies between Closely Related Arenaviruses. J Virol 91:|
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