This is a revised application for postdoctoral training in clinical immunology and rheumatology designed to foster rigorous training in technology transfer and clinical investigation to physician scientists in clinical immunology/rheumatology. This multidisciplinary program requests support for two new postdoctoral trainees yearly for the Division of Immunology and Rheumatology as well as one new trainee yearly for the Division of Pediatric Rheumatology at Stanford University Medical School. The faculty's research is at the forefront of key areas in modern molecular, cellular, and clinical immunology and clinical research and investigation and into the outcomes associated with rheumatas ic diseases and their treatment. The Divisions' faculty are leaders in the development of new technologies and in the application of current knowledge of basic immune mechanisms to the investigation and treatment of rheumatic diseases as well as in the assessment of the outcomes of these therapies. The research and training activities of this Program will benefit from the multidisciplinary approach of the faculty and the tradition of interaction among the adult and pediatric rheumatologists/immunologists. Previous postdoctoral trainees have come from top internal medicine and/or pediatric residencies. Trainees will develop basic science and clinical investigation skills either in the laboratory or through interaction with and participation in program activities, including a weekly seminar series, journal club, and an annual Immunology retreat. Trainees will be required to present their work at the retreat and will be encouraged to present their research at one national meeting per year. Trainees will have access to modern, state-of-the-art research facilities dedicated to clinical investigation or to molecular and cellular immunology. This application seeks support for 3 postdoctoral trainees in year one increasing to a steady state of 9 trainees by year three. It is expected that one pediatrician and two internists will be admitted per year, each for a three year fellowship that can include a laboratory component or training in health services research or clinical investigation. Clinical responsibilities and training within the proposed program are described below. The training program will be under the direction of C. Garrison Fathman, M.D., as PI. Alan Krensky M.D., Mark Genovese M.D., Christy Sandborg M.D., Halstead Holman M.D. and Jim Fries M.D. will serve as co-PIs. The ultimate goal of this training program is the development of outstanding physician-scientists in the area of basic or clinical investigations in immunology and rheumatology.

National Institute of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Program Officer
Gretz, Elizabeth
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Stanford University
Internal Medicine/Medicine
Schools of Medicine
United States
Zip Code
Geraldino-Pardilla, Laura; Russo, Cesare; Sokolove, Jeremy et al. (2017) Association of anti-citrullinated protein or peptide antibodies with left ventricular structure and function in rheumatoid arthritis. Rheumatology (Oxford) 56:534-540
Moskowitz, David M; Zhang, David W; Hu, Bin et al. (2017) Epigenomics of human CD8 T cell differentiation and aging. Sci Immunol 2:
Sokolove, Jeremy; Schiff, Michael; Fleischmann, Roy et al. (2016) Impact of baseline anti-cyclic citrullinated peptide-2 antibody concentration on efficacy outcomes following treatment with subcutaneous abatacept or adalimumab: 2-year results from the AMPLE trial. Ann Rheum Dis 75:709-14
Macaubas, Claudia; Wong, Elizabeth; Zhang, Yujuan et al. (2016) Altered signaling in systemic juvenile idiopathic arthritis monocytes. Clin Immunol 163:66-74
Yiu, Gloria; Rasmussen, Tue K; Ajami, Bahareh et al. (2016) Development of Th17-Associated Interstitial Kidney Inflammation in Lupus-Prone Mice Lacking the Gene Encoding STAT-1. Arthritis Rheumatol 68:1233-44
Postolova, Anna; Chen, Jennifer K; Chung, Lorinda (2016) Corticosteroids in Myositis and Scleroderma. Rheum Dis Clin North Am 42:103-18, ix
Cho, Hyunje Grace; Fiorentino, David; Lewis, Matthew et al. (2016) Identification of Alpha-Adrenergic Agonists as Potential Therapeutic Agents for Dermatomyositis through Drug-Repurposing Using Public Expression Datasets. J Invest Dermatol 136:1517-1520
Bernet, Laura L; Lewis, Matthew A; Rieger, Kerri E et al. (2016) Ovoid Palatal Patch in Dermatomyositis: A Novel Finding Associated With Anti-TIF1? (p155) Antibodies. JAMA Dermatol 152:1049-51
Corey, Daniel M; Rosental, Benyamin; Kowarsky, Mark et al. (2016) Developmental cell death programs license cytotoxic cells to eliminate histocompatible partners. Proc Natl Acad Sci U S A 113:6520-5
Sokolove, Jeremy; Wagner, Catriona A; Lahey, Lauren J et al. (2016) Increased inflammation and disease activity among current cigarette smokers with rheumatoid arthritis: a cross-sectional analysis of US veterans. Rheumatology (Oxford) 55:1969-1977

Showing the most recent 10 out of 46 publications