The goal of this application is to establish a postdoctoral fellowship program in investigative dermatology and cutaneous biology at the University of Alabama at Birmingham (UAB) to train promising M.D., M.D./Ph.D. and Ph.D.'s for investigative careers in academic dermatology. Funding is requested for two positions in the first year and a total of four positions in the following years. UAB is an institution with a distinguished record for providing a truly outstanding training environment in which cooperation among researchers from different disciplines is the model. Based in the Department of Dermatology, which has made significant progress in developing programs of excellence in dermatological research, the program will provide interdisciplinary training to talented individuals who are interested in becoming independent researchers in either basic or clinical/translational research in skin diseases. Qualified individuals who are accepted into the program will receive mentor based training in one of a variety of areas relevant to dermatology. The faculty that will serve as mentors all have successful independently-funded research programs in disciplines directly related to investigative dermatology and cutaneous biology and have impressive track records in interdisciplinary research and in the preparation of postdoctoral fellows for successful research-oriented academic careers. Each trainee will have both a primary and secondary mentor to oversee his/her training. In most instances, one of these will be within dermatology and the other outside of the Department, thereby allowing for inclusion of mentors conducting skin-related research in other departments. This will provide the trainee with exposure to new scientific skills while at the same time maintaining a link and ensuring that the training experience has relevance to dermatology. The UAB Skin Diseases Research Center will be a valuable resource for trainees, providing them with Core facilities to assist with their research and an active Enrichment program that will facilitate interactions with other investigators at this University. In addition to mentor based research projects, trainees will participate in didactic activities that will strengthen the intellectual foundation required for innovative dermatological projects and will also receive rigorous instruction in the principles necessary for ethical research. The ultimate goal of this program will be to provide superior training for the next generation of academic researchers in investigative dermatology.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32AR053458-05
Application #
7810627
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Program Officer
Cibotti, Ricardo
Project Start
2006-05-01
Project End
2012-04-30
Budget Start
2010-05-01
Budget End
2012-04-30
Support Year
5
Fiscal Year
2010
Total Cost
$218,538
Indirect Cost
Name
University of Alabama Birmingham
Department
Dermatology
Type
Schools of Medicine
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Palmer, Matthew T; Weaver, Casey T (2013) Linking vitamin d deficiency to inflammatory bowel disease. Inflamm Bowel Dis 19:2245-56
Buster, Kesha J; Stevens, Erica I; Elmets, Craig A (2012) Dermatologic health disparities. Dermatol Clin 30:53-9, viii
Palmer, Matthew T; Lee, Yun Kyung; Maynard, Craig L et al. (2011) Lineage-specific effects of 1,25-dihydroxyvitamin D(3) on the development of effector CD4 T cells. J Biol Chem 286:997-1004
Camp, William L; Turnham, Jennifer W; Athar, Mohammad et al. (2011) New agents for prevention of ultraviolet-induced nonmelanoma skin cancer. Semin Cutan Med Surg 30:6-13
Walsh, Stephanie B; Xu, Jianmin; Xu, Hui et al. (2011) Cyclosporine a mediates pathogenesis of aggressive cutaneous squamous cell carcinoma by augmenting epithelial-mesenchymal transition: role of TGF? signaling pathway. Mol Carcinog 50:516-27
Athar, Mohammad; Walsh, Stephanie B; Kopelovich, Levy et al. (2011) Pathogenesis of nonmelanoma skin cancers in organ transplant recipients. Arch Biochem Biophys 508:159-63
Byekova, Yevgeniya A; Herrmann, Jennifer L; Xu, Jianmin et al. (2011) Liver kinase B1 (LKB1) in the pathogenesis of UVB-induced murine basal cell carcinoma. Arch Biochem Biophys 508:204-11
Xu, Jianmin; Walsh, Stephanie B; Verney, Zoe M et al. (2011) Procarcinogenic effects of cyclosporine A are mediated through the activation of TAK1/TAB1 signaling pathway. Biochem Biophys Res Commun 408:363-8
Holzer, Aton M; Athar, Mohammad; Elmets, Craig A (2010) The other end of the rainbow: infrared and skin. J Invest Dermatol 130:1496-9
Thacker, Erin E; Nakayama, Masaharu; Smith, Bruce F et al. (2009) A genetically engineered adenovirus vector targeted to CD40 mediates transduction of canine dendritic cells and promotes antigen-specific immune responses in vivo. Vaccine 27:7116-24

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