This is the third competitive renewal for T32DA013911 (?HIV and Other Infectious Consequences of Substance Abuse?) and seeks funding for Years 2017-2022. The program will now be led by dual PIs: Dr. Timothy P. Flanigan (the PI for the past 15 years), who will direct mentoring and training, and Dr. Josiah D. Rich, who will direct research project development. This training grant focuses on applied clinical and substance use research in Rhode Island and beyond. Rhode Island has among the highest rates of substance use in the nation and ranks 6th in the country for overdose rates. Our substance use training program emerged from the Brown University-affiliated Miriam Hospital Immunology Center, the largest HIV care center in Southern New England, where approximately 60% of the patients engage in substance use (alcohol, cocaine, opiate, methamphetamines, and poly-substance abuse). Our program's strengths are our interdisciplinary collaborations to reduce the infectious disease consequences of substance use, including HIV, hepatitis B and C, sexually transmitted infections, and TB. This training program brings together core expertise from the Division of Infectious Diseases, the Providence-Boston Center for AIDS Research (CFAR), the Centers for Behavioral and Preventive Medicine, the Brown University Center for Statistical Studies, and the Brown University School of Public Health. This interdisciplinary training program focuses on HIV prevention and treatment, including innovative PrEP programs, and correctional health, with a primary focus on reducing the infectious consequences of substance use as well as overdose. Our mentors have strong track records in applied clinical, substance use, translational science, correctional health research, and community-engaged scholarship.

Public Health Relevance

This program trains post-doctoral fellows in clinical research to more effectively understand and manage the challenges of HIV and other infectious consequences of substance abuse. Incorporating expertise from multiple disciplines greatly enhances diagnosis, prevention and treatment research of HIV and other infectious diseases among active substance abusers and within communities that are heavily impacted by substance abuse. Community engagement is emphasized to ensure that marginalized communities benefit from advances in biomedical science.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Institutional National Research Service Award (T32)
Project #
2T32DA013911-16A1
Application #
9348800
Study Section
Special Emphasis Panel (ZAA1)
Program Officer
Mandler, Raul N
Project Start
2001-07-01
Project End
2022-06-30
Budget Start
2017-07-01
Budget End
2018-06-30
Support Year
16
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Miriam Hospital
Department
Type
DUNS #
063902704
City
Providence
State
RI
Country
United States
Zip Code
02906
Ammon, Benjamin; Iroh, Princess; Tiruneh, Yordanos et al. (2018) HIV Care After Jail: Low Rates of Engagement in a Vulnerable Population. J Urban Health 95:488-498
Reece, Rebecca; Delong, Allison; Matthew, D'Antuono et al. (2018) Accumulated pre-switch resistance to more recently introduced one-pill-once-a-day antiretroviral regimens impacts HIV-1 virologic outcome. J Clin Virol 105:11-17
Stone, Andrew C; Carroll, Jennifer J; Rich, Josiah D et al. (2018) Methadone maintenance treatment among patients exposed to illicit fentanyl in Rhode Island: Safety, dose, retention, and relapse at 6 months. Drug Alcohol Depend 192:94-97
Oldenburg, Catherine E; Perez-Brumer, Amaya G; Reisner, Sari L et al. (2018) Human rights protections and HIV prevalence among MSM who sell sex: Cross-country comparisons from a systematic review and meta-analysis. Glob Public Health 13:414-425
Carroll, Jennifer J; Rich, Josiah D; Green, Traci C (2018) Reducing Collateral Damage in Responses to the Opioid Crisis. Am J Public Health 108:349-350
Dauria, Emily; Tolou-Shams, Marina; Skipalska, Halyna et al. (2018) Outcomes of the ""STEPS"" HIV prevention training program for young males in the penitentiary institution, Ukraine. Int J Prison Health 14:101-108
Brinkley-Rubinstein, Lauren; Macmadu, Alexandria; Marshall, Brandon D L et al. (2018) Risk of fentanyl-involved overdose among those with past year incarceration: Findings from a recent outbreak in 2014 and 2015. Drug Alcohol Depend 185:189-191
Oldenburg, Catherine E; Nunn, Amy S; Montgomery, Madeline et al. (2018) Behavioral Changes Following Uptake of HIV Pre-exposure Prophylaxis Among Men Who Have Sex with Men in a Clinical Setting. AIDS Behav 22:1075-1079
Ortblad, Katrina F; Musoke, Daniel K; Ngabirano, Thomson et al. (2018) Female Sex Workers Often Incorrectly Interpret HIV Self-Test Results in Uganda. J Acquir Immune Defic Syndr 79:e42-e45
Sakyi, Kwame S; Lartey, Margaret Y; Dension, Julie A et al. (2018) Low Birthweight, Retention in HIV Care, and Adherence to ART Among Postpartum Women Living with HIV in Ghana. AIDS Behav :

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