This is a new application from the College of Dental Medicine at the Medical University of South Carolina (MUSC) that requests (1) continued NIDCR support for a summer research training program for dental students with a proven record of success;(2) support for a Dual Degree (DMD/PhD) Program established with institutional funds, which also has a proven record of success;and (3) support for a new Postdoctoral Research Program that will address a gap in a comprehensive roster of oral and craniofacial research training opportunities at MUSC. The full complement of research training options is enhanced by other NIH and institutionally supported programs at MUSC that offer research career development tracks for junior dental faculty (notably the NCRR P20 """"""""COBRE"""""""" and NIDCR U24 awards) and an NIH Roadmap T32 award for predoctoral training in clinical research. Included in this proposal is a Progress Report summarizing relevant research training achievements to date as proof of principle and documentation. The overarching objective of the proposed Dental Research Training Program (DRTP) is to train an interdisciplinary cadre of talented investigators for careers in dental, oral and craniofacial science who will become the next generation of dental school faculty and provide academic leadership in the nation's dental, oral and craniofacial research programs. Mentoring and training activities are thematically grouped in five strategic areas of research focus: (i) infection and immunity, (ii) oral and systemic health, (iii) oral cancer, (iv) regenerative medicine/bioengineering, and (v) proteomics. Integrative training components, including an Oral Health Journal Club, Seminar Series, and Student Research Day, provide a framework for all trainees to interact, collaborate, and work together during their training experience. The proposed program benefits from the excellent administrative support and institutional commitment already in place and operating effectively in the Center for Oral Health Research. An integrated multi-year evaluation plan will be used to measure the extent to which the program goals and objectives are met.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Institutional National Research Service Award (T32)
Project #
5T32DE017551-05
Application #
7882323
Study Section
Special Emphasis Panel (ZDE1-LK (28))
Program Officer
Hardwick, Kevin S
Project Start
2006-07-01
Project End
2011-06-30
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
5
Fiscal Year
2010
Total Cost
$456,303
Indirect Cost
Name
Medical University of South Carolina
Department
Microbiology/Immun/Virology
Type
Schools of Dentistry
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425
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Lee, Jungnam; Roberts, JoAnn S; Atanasova, Kalina R et al. (2017) Human Primary Epithelial Cells Acquire an Epithelial-Mesenchymal-Transition Phenotype during Long-Term Infection by the Oral Opportunistic Pathogen, Porphyromonas gingivalis. Front Cell Infect Microbiol 7:493
Wei, F; Van Horn, M H; Coombs, M C et al. (2017) A pilot study of nocturnal temporalis muscle activity in TMD diagnostic groups of women. J Oral Rehabil 44:517-525
Atanasova, Kalina; Lee, Jungnam; Roberts, JoAnn et al. (2016) Nucleoside-Diphosphate-Kinase of P. gingivalis is Secreted from Epithelial Cells In the Absence of a Leader Sequence Through a Pannexin-1 Interactome. Sci Rep 6:37643

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