The training program in Pediatric Nephrology at the Albert Einstein College of Medicine provides the clinical and research experience to foster development of new Pediatric Nephrology investigators who will meet the academic workforce needs of this subspecialty. Graduates can diagnose and manage pediatric renal diseases, especially with regards to health disparities for underserved populations, understand the physiology of fluid and electrolyte regulation, with emphasis on the development and maturation of the kidney, and acquire scientific skills necessary for a career as an independent physician-investigator. In the past 40 years over 100 graduates of the program have remained in academic medicine and continue their research contributions. Clinical research projects involve: immunosuppression and allograft rejection in pediatric renal transplantation, mechanisms of bone disease and growth retardation, and disturbances in nitric oxide in hypertension. Experience in basic research is designed to elucidate the cellular and molecular mechanisms responsible for renal cell growth, proliferation, differentiation and apoptosis. Continued collaboration with the Division of Nephrology in the Department of Medicine provides opportunities for research and education that has fostered the career development of numerous trainees. Combined conferences in clinical and basic research areas in nephrology facilitate the trainee's acquisition of knowledge and appreciation of the importance of critical scientific analysis. Required courses in renal physiology and pathophysiology, research design, biostatistics, renal pathology and bioethics, and the opportunity to enroll in a Masters' Program in Clinical Investigation, complement the trainee's three years of experience.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
2T32DK007110-27
Application #
6411304
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Rankin, Tracy L
Project Start
1976-07-01
Project End
2007-06-30
Budget Start
2002-07-01
Budget End
2003-06-30
Support Year
27
Fiscal Year
2002
Total Cost
$212,556
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Pediatrics
Type
Schools of Medicine
DUNS #
009095365
City
Bronx
State
NY
Country
United States
Zip Code
10461
Reidy, Kimberly J; Hjorten, Rebecca; Parekh, Rulan S (2018) Genetic risk of APOL1 and kidney disease in children and young adults of African ancestry. Curr Opin Pediatr 30:252-259
Reidy, Kimberly J; Hjorten, Rebecca C; Simpson, Claire L et al. (2018) Fetal-Not Maternal-APOL1 Genotype Associated with Risk for Preeclampsia in Those with African Ancestry. Am J Hum Genet 103:367-376
Dogra, Samriti; Kaskel, Frederick (2017) Steroid-resistant nephrotic syndrome: a persistent challenge for pediatric nephrology. Pediatr Nephrol 32:965-974
Chen, Wei; Melamed, Michal L; Hostetter, Thomas H et al. (2016) Effect of oral sodium bicarbonate on fibroblast growth factor-23 in patients with chronic kidney disease: a pilot study. BMC Nephrol 17:114
Sarathy, Harini; Henriquez, Gabriela; Abramowitz, Matthew K et al. (2016) Abdominal Obesity, Race and Chronic Kidney Disease in Young Adults: Results from NHANES 1999-2010. PLoS One 11:e0153588
Uy, Natalie; Graf, Lauren; Lemley, Kevin V et al. (2015) Effects of gluten-free, dairy-free diet on childhood nephrotic syndrome and gut microbiota. Pediatr Res 77:252-5
Dogra, Samriti; Bandi, Sriram; Viswanathan, Preeti et al. (2015) Arsenic trioxide amplifies cisplatin toxicity in human tubular cells transformed by HPV-16 E6/E7 for further therapeutic directions in renal cell carcinoma. Cancer Lett 356:953-61
Becton, Lauren J; Goilav, Beatrice; Wang, Yanhua et al. (2015) An 18-year-old with nephrotic syndrome and chest pain: questions. Pediatr Nephrol 30:267, 269-71
Chen, Wei; Melamed, Michal L; Abramowitz, Matthew K (2015) Serum bicarbonate and bone mineral density in US adults. Am J Kidney Dis 65:240-8
Chen, Wei; Abramowitz, Matthew K (2014) Metabolic acidosis and the progression of chronic kidney disease. BMC Nephrol 15:55

Showing the most recent 10 out of 50 publications