The Training Program in Nephrology at the University of Michigan is designed to prepare post-doctoral trainees with either M.D. or Ph.D. degrees for a career in basic, epidemiology/outcomes or clinical Nephrology research. Training will be carefully designed and individually tailored for each trainee and will combine a didactic program with a mentored research experience. The proposed Training Program will provide 2 or more years of postdoctoral research training in Nephrology to MD trainees in 3 areas: a) basic laboratory research, including biomedical engineering research;b) outcomes and epidemiology research or clinical research;and c) systems biology. Ph.D. trainees will receive intensive basic laboratory or biomedical engineering research training. Four trainees will be appointed yearly. The Training Program will be provided by 36 faculty members from 14 departments and 3 schools/colleges, all of whom have substantial training experience. Given the considerable scientific collaboration among the various members of the Program Faculty, there will be ample opportunity for a given trainee to gain research experience in more than one research setting during his or her training experience. Trainees will enroll in intensive didactic programs depending on their research track. Those in the basic science track will complete a three month Postgraduate Research Training Program. Those in the clinical research or epidemiology/outcomes track will complete a Masters of Public Health program in Biostatistics and Epidemiology or a Masters of Science program in the Clinical Research Design and Statistical Analysis course. Those in the systems biology track will have the option of completing a Masters Degree in Bioinformatics or an introductory course in systems biology. Weekly seminar series conducted by the Training Program will complement the formal curricula. Based on this training and the excellent track record of graduates from the Training Program in Nephrology, fellows will be well positioned for independent careers in Nephrology research.

Public Health Relevance

The future of nephrology as a discipline and the advancement of nephrology as a science are dependent on our ability as a community to recruit, well educate, and retain talented individuals. The T32 Training Program in Nephrology at that University of Michigan has demonstrated outstanding success in this mission over 25 years and will continue to provide an outstanding training resource for this purpose in the future.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
2T32DK007378-31
Application #
7849830
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Rankin, Tracy L
Project Start
1980-07-01
Project End
2015-06-30
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
31
Fiscal Year
2010
Total Cost
$286,576
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Crawford, Brendan D; Gillies, Christopher E; Robertson, Catherine C et al. (2017) Evaluating Mendelian nephrotic syndrome genes for evidence for risk alleles or oligogenicity that explain heritability. Pediatr Nephrol 32:467-476
Beamish, Jeffrey A; Chen, Evan; Putnam, Andrew J (2017) Engineered extracellular matrices with controlled mechanics modulate renal proximal tubular cell epithelialization. PLoS One 12:e0181085
Sampson, Matthew G; Gillies, Christopher E; Robertson, Catherine C et al. (2016) Using Population Genetics to Interrogate the Monogenic Nephrotic Syndrome Diagnosis in a Case Cohort. J Am Soc Nephrol 27:1970-83
Gillies, Christopher E; Otto, Edgar A; Vega-Warner, Virginia et al. (2016) tarSVM: Improving the accuracy of variant calls derived from microfluidic PCR-based targeted next generation sequencing using a support vector machine. BMC Bioinformatics 17:233
Afshinnia, Farsad; Zaky, Ziad S; Metireddy, Manasa et al. (2016) Reverse Epidemiology of Blood Pressure in Peritoneal Dialysis Associated with Dynamic Deterioration of Left Ventricular Function. Perit Dial Int 36:154-62
Afshinnia, F; Sundaram, B; Ackermann, R J et al. (2015) Hyponatremia and osteoporosis: reappraisal of a novel association. Osteoporos Int 26:2291-8
Spinale, Joann M; Mariani, Laura H; Kapoor, Shiv et al. (2015) A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular disease. Kidney Int 87:564-74
Lai, Jennifer Y; Luo, Jinghui; O'Connor, Christopher et al. (2015) MicroRNA-21 in glomerular injury. J Am Soc Nephrol 26:805-16
Yang, Yan; Hodgin, Jeffrey B; Afshinnia, Farsad et al. (2015) The two kidney to one kidney transition and transplant glomerulopathy: a podocyte perspective. J Am Soc Nephrol 26:1450-65
Soranno, Danielle E; Lu, Hoang D; Weber, Heather M et al. (2014) Immunotherapy with injectable hydrogels to treat obstructive nephropathy. J Biomed Mater Res A 102:2173-80

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