For more than 30 years, the Integrated Training Program in Diabetes, Endocrinology and Metabolism (DEM) has supported and enhanced research training in DEM for predoctoral and postdoctoral trainees at University of California San Francisco. Track 1, the predoctoral training path, operates with the UCSF Biomedical Sciences Graduate Program, which trains students for research careers investigating basic mechanisms of human physiology and disease, to integrate training and strengthen opportunities for graduate students interested in research careers in DEM. Postoctoral training includes two tracks. Track 2 supports mentored postdoctoral research training in DEM. Track 3 combines clinical and research training for physician-scientists. Postdoctoral trainees in Track 2 or 3 may train in the Basic Investigator or Clinical Investigator Pathways. Both pathways provide a combination of didactic (seminars, lectures, journal clubs) and individually-mentored research training. Training for Clinical Investigators includes courses in Epidemiology, Biostatistics, and Clinical Study Design. All predoctoral and postdoctoral DEM trainees participate in seminars on the Ethics and Responsible Conduct of Science. Trainees work with a large, accomplished, and interactive DEM faculty drawn from 13 academic departments and 7 Organized Research Units/Institutes across UCSF. The majority (91%) of the predoctoral trainees who have earned their PhDs are now in postdoctoral research fellowships or academic research faculty positions. Of the postdoctoral trainees who completed their fellowships during this funding period, 69% hold academic faculty positions, and 59% remain in research. New improvements to the DEM Program include a formal Career Mentoring Program, a new summer research program for medical students, an annual retreat, increased integration with the NIH/NIDDK-supported UCSF Diabetes and Endocrinology Center (DERC) and expansion to the new basic science campus at UCSF Mission Bay. Together these changes enhance the already strong DEM Training Program and will expand future opportunities in DEM for both predoctoral and postdoctoral trainees at UCSF.

Public Health Relevance

The Integrated Training Program in Diabetes, Endocrinology and Metabolism (DEM) enhances research training in Endocrinology and Metabolism at University of California San Francisco (UCSF) by supporting didactic education, mentored research experience and career mentoring for scientists in training. Research performed by scientists trained through the UCSF DEM Program contributes to our understanding of endocrine and metabolic diseases and to improvements in the lives of people suffering from these disorders.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007418-34
Application #
8728800
Study Section
Special Emphasis Panel (ZDK1-GRB-J (J1))
Program Officer
Castle, Arthur
Project Start
1981-07-01
Project End
2016-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
34
Fiscal Year
2014
Total Cost
$507,617
Indirect Cost
$36,926
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Alba, Diana L; Farooq, Jeffrey A; Lin, Matthew Y C et al. (2018) Subcutaneous Fat Fibrosis Links Obesity to Insulin Resistance in Chinese Americans. J Clin Endocrinol Metab 103:3194-3204
Hasegawa, Yutaka; Ikeda, Kenji; Chen, Yong et al. (2018) Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis. Cell Metab 27:180-194.e6
Mocciaro, Annamaria; Roth, Theodore L; Bennett, Hayley M et al. (2018) Light-activated cell identification and sorting (LACIS) for selection of edited clones on a nanofluidic device. Commun Biol 1:41
Lee, Jessica; Pappalardo, Zachary; Chopra, Deeksha Gambhir et al. (2018) A Genetic Interaction Map of Insulin Production Identifies Mfi as an Inhibitor of Mitochondrial Fission. Endocrinology 159:3321-3330
Roth, Theodore L; Puig-Saus, Cristina; Yu, Ruby et al. (2018) Reprogramming human T cell function and specificity with non-viral genome targeting. Nature 559:405-409
Mongraw-Chaffin, Morgana; Gujral, Unjali P; Kanaya, Alka M et al. (2018) Relation of Ectopic Fat with Atherosclerotic Cardiovascular Disease Risk Score in South Asians Living in the United States (from the Mediators of Atherosclerosis in South Asians Living in America [MASALA] Study). Am J Cardiol 121:315-321
Byrnes, Lauren E; Wong, Daniel M; Subramaniam, Meena et al. (2018) Lineage dynamics of murine pancreatic development at single-cell resolution. Nat Commun 9:3922
Anderton, Brittany; Camarda, Roman; Balakrishnan, Sanjeev et al. (2017) MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer. EMBO Rep 18:569-585
Rushakoff, Robert J; Sullivan, Mary M; MacMaster, Heidemarie Windham et al. (2017) Association Between a Virtual Glucose Management Service and Glycemic Control in Hospitalized Adult Patients: An Observational Study. Ann Intern Med 166:621-627
Mongraw-Chaffin, Morgana; Kanaya, Alka M; Kandula, Namratha R et al. (2017) The relationship between anthropometry and body composition from computed tomography: The Mediators of Atherosclerosis in South Asians Living in America Study. Ethn Health 22:565-574

Showing the most recent 10 out of 110 publications