This is a competing continuing application to support the post-doctoral research Training Program in Diabetes, Endocrinology and Metabolism (TPDEM) at the University of Colorado at Denver and Health Sciences Center (UCDHSC). The TPDEM is the only NIH funded adult endocrine research training program between the west-coast states of California, Oregon and Washington and the mid-western states of Minnesota, Illinois, Missouri and Texas, an area covering one third of the United States land mass. This TPDEM has been continuously funded since 1982, and directed by Dr. E. Chester Ridgway since 1985. This grant currently supports seven (7) postdoctoral trainees per year. Typically, six positions are utilized by adult MD fellows who have completed one year of clinical training in adult endocrinology prior to beginning the TPDEM. Usually one position per year is provided to an MD Fellow who is part of the Pediatric Endocrinology Training Program, and who performs endocrine research which is not covered by the Training Program in Diabetes Research at the Barbara Davis Center for Childhood Diabetes. Occasionally one position is used for a PhD fellow. The TPDEM provides intensive, diverse mentored training in endocrine research disciplines ranging from the molecular and cellular biology of hormone action to the epidemiology of diabetes and community based interventions for obesity. The training environment at UCDHSC provides a wealth of resources for potential trainees. These include the Barbara Davis Center for Childhood Diabetes, the Center for Human Nutrition, the University of Colorado Cancer Center, and the General Clinical Research Centers at both the Denver Children's Hospital and University of Colorado Hospital just to name a few. UCDHSC is investing over 4.3 billion dollars into a new state of the art campus at Fitzsimons with an adjacent Bioscience Research Park that will foster translation of basic research advances into clinical practice. The 48 members of the Training Faculty include senior, mid-career and junior investigators, many of whom are nationally recognized leaders in their fields of study. This training grant has supported 24 fellows over the last 5 years. From this group, a total of 7 K-series or equivalent (VA, ACS) Career Development Awards and 2 individual NRSAs have been awarded. Twenty of 24 are still doing research. Overall, this outstanding training environment and excellent record of accomplishment justify continued support of the TPDEM at UCDHSC.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007446-30
Application #
8100323
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Castle, Arthur
Project Start
1982-07-01
Project End
2012-06-30
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
30
Fiscal Year
2011
Total Cost
$335,527
Indirect Cost
Name
University of Colorado Denver
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Patel, Sonali S; Truong, Uyen; King, Martina et al. (2017) Obese adolescents with polycystic ovarian syndrome have elevated cardiovascular disease risk markers. Vasc Med 22:85-95
Cree-Green, Melanie; Cai, Ninghe; Pyle, Laura et al. (2017) Insulin Resistance in Youth Without Diabetes Is Not Related to Muscle Mitochondrial Dysfunction. J Clin Endocrinol Metab 102:1652-1660
Swanson, Christine M; Shea, Steven A; Wolfe, Pamela et al. (2017) Bone Turnover Markers After Sleep Restriction and Circadian Disruption: A Mechanism for Sleep-Related Bone Loss in Humans. J Clin Endocrinol Metab 102:3722-3730
Park, Young-Min; Pereira, Rocio I; Erickson, Christopher B et al. (2017) Time since menopause and skeletal muscle estrogen receptors, PGC-1?, and AMPK. Menopause 24:815-823
Park, Young-Min; Erickson, Christopher; Bessesen, Dan et al. (2017) Age- and menopause-related differences in subcutaneous adipose tissue estrogen receptor mRNA expression. Steroids 121:17-21
Johnson, Richard J; Stenvinkel, Peter; Jensen, Thomas et al. (2016) Metabolic and Kidney Diseases in the Setting of Climate Change, Water Shortage, and Survival Factors. J Am Soc Nephrol 27:2247-56
Roncal-Jimenez, C; Lanaspa, M A; Jensen, T et al. (2015) Mechanisms by Which Dehydration May Lead to Chronic Kidney Disease. Ann Nutr Metab 66 Suppl 3:10-3
Pereira, R I; Casey, B A; Swibas, T A et al. (2015) Timing of Estradiol Treatment After Menopause May Determine Benefit or Harm to Insulin Action. J Clin Endocrinol Metab 100:4456-62
Swanson, Christine M; Srikanth, Priya; Lee, Christine G et al. (2015) Associations of 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D With Bone Mineral Density, Bone Mineral Density Change, and Incident Nonvertebral Fracture. J Bone Miner Res 30:1403-13
Thomas, Elizabeth A; Higgins, Janine; Bessesen, Daniel H et al. (2015) Usual breakfast eating habits affect response to breakfast skipping in overweight women. Obesity (Silver Spring) 23:750-9

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