Our surgical research program will provide young surgical residents a unique, intensive and interdisciplinary training experience in one of two tracks for scholarly investigations in surgical diseases of the alimentary tract, liver, and pancreas: 1) the basic science track, which provides the individual trainee a structured research experience in the fundamental aspects of biomedical research, including aspects of molecular biology, physiology, biochemistry, endocrinology, pharmacology, and immunology and cell biology, or 2) the epidemiology, outcomes, and health services track, which provides formal training in biostatistics and epidemiology as they pertain to surgical diseases of the digestive tract. Two trainees will be enrolled in the first track have the opportunity also to obtain a Maste in Medical Science, which will include writing a proposal and final dissertation on their research project. One trainee will earn a Master in Clinical Science and will gain proficiency in the skills necessary to become independent investigators in the field of comparative effective and health services research including basic and advanced biostatistics, large dataset analysis, use of administrative data (e.g., Medicare and SEER-Medicare databases), clinical epidemiology, health policy, and healthcare economics. Each trainee will dedicate 2-3 years of laboratory and education time free of clinical duties to pursue their investigations. The primary goal of our two-track program is to prepare surgical residents to become independent and successful academic surgeons, whether they choose the path of surgeon-scientist or public health researcher. The research interests of our faculty members all center on the theme of gastrointestinal diseases, including the liver and pancreas, with a predominance on the study of cancer and inflammation. Our trainees are provided a diverse research experience, encouraged to select secondary career mentors and engage in pre-existing interdepartmental collaborations.
The UTMB gastrointestinal training program provides general surgical residents-in-training a solid foundation to become independent scientists in the field of basic biomedical research or outcomes research as it pertains to diseases of the GI tract, liver, or pancreas. The future betterment and care of the surgical patient with inflammation and/or cancer of the alimentary tract, liver, and pancreas depends on understanding basic mechanisms of disease, as well as comparative effectiveness and health services research.
|Tamirisa, Nina P; Sheffield, Kristin M; Parmar, Abhishek D et al. (2015) Surgeon and Facility Variation in the Use of Minimally Invasive Breast Biopsy in Texas. Ann Surg 262:171-8|
|Cooper, Amanda B; Parmar, Abhishek D; Riall, Taylor S et al. (2015) Does the use of neoadjuvant therapy for pancreatic adenocarcinoma increase postoperative morbidity and mortality rates? J Gastrointest Surg 19:80-6; discussion 86-7|
|Parmar, Abhishek D; Sheffield, Kristin M; Adhikari, Deepak et al. (2015) PREOP-Gallstones: A Prognostic Nomogram for the Management of Symptomatic Cholelithiasis in Older Patients. Ann Surg 261:1184-90|
|Mrazek, Amy A; Chao, Celia (2014) Surviving cutaneous melanoma: a clinical review of follow-up practices, surveillance, and management of recurrence. Surg Clin North Am 94:989-1002, vii-viii|
|Mrazek, Amy A; Carmical, Joseph R; Wood, Thomas G et al. (2014) Colorectal Cancer-Associated Fibroblasts are Genotypically Distinct. Curr Cancer Ther Rev 10:97-218|
|Chen, Haijun; Mrazek, Amy A; Wang, Xiaofu et al. (2014) Design, synthesis, and characterization of novel apigenin analogues that suppress pancreatic stellate cell proliferation in vitro and associated pancreatic fibrosis in vivo. Bioorg Med Chem 22:3393-404|
|Parmar, Abhishek D; Vargas, Gabriela M; Tamirisa, Nina P et al. (2014) Trajectory of care and use of multimodality therapy in older patients with pancreatic adenocarcinoma. Surgery 156:280-9|
|Vargas, Gabriela M; Parmar, Abhishek D; Sheffield, Kristin M et al. (2014) Impact of liver-directed therapy in colorectal cancer liver metastases. J Surg Res 191:42-50|
|Vargas, Gabriela M; Sheffield, Kristin M; Parmar, Abhishek D et al. (2014) Trends in treatment and survival in older patients presenting with stage IV colorectal cancer. J Gastrointest Surg 18:369-77|
|Djukom, Clarisse; Porro, Laura J; Mrazek, Amy et al. (2014) Dual inhibition of PI3K and mTOR signaling pathways decreases human pancreatic neuroendocrine tumor metastatic progression. Pancreas 43:88-92|
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