The Renal Epidemiology Training Program prepares trainees to design, conduct, and analyze independent research in the expansive field of kidney disease in collaboration with faculty in the UNC Kidney Center (UNCKC), the Department of Epidemiology and other UNC schools and departments. The UNCKC, whose director Dr. Ronald Falk reports directly to the CEO and Dean of the UNC Healthcare System, allows for an integrated approach to research and education. The UNCKC includes members in the Schools of Medicine, Public Health, Dentistry, Pharmacology, and the College of Arts and Sciences. In this over-arching structure, trainees have the opportunity to obtain their Masters of Public Health (MPH), PhD, or design and implement other structured training. Guidance is provided by mentoring teams comprised of faculty with expertise and established collaborative research interests across diverse areas of current interest in the realm of kidney research including epidemiology, immunology, genetics, pathology, pharmacology, health policy and more. Faculty have special expertise in systemic diseases that affect the kidney, including lupus, vasculitis, diabetes, and hypertension. Access to study populations is available through clinics and existing study databases, such as the Atherosclerosis Risk in Communities (ARIC) study and the Strong Heart Study. The academic curriculum is supplemented by a structured schedule of seminars, conferences, performance reviews and close interaction with faculty. Trainees are well-informed about the scope and impact of areas of research needed in the field of kidney disease, and work with faculty mentoring teams to review the literature, develop research initiatives, conduct and analyze data, and prepare abstracts, research presentations, manuscripts and grants. This program began in 1998 with one post-doctoral trainee and has expanded to three post-doctoral (one minority supplement for 2006-2008) and two pre-doctoral candidates. The post doctoral program includes both adult and pediatric trainees. Eight of 9 post-doctoral trainees and all 3 pre-doctoral candidates have degrees from prestigious U.S. universities. One of the post-doctoral and 2/3 of our pre-doctoral trainees are from underrepresented minorities. Six candidates have completed their training, with five now in faculty positions at excellent academic medical centers and one in industry. All trainees have published manuscripts or manuscripts underway for a total of 103 manuscripts.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (ZDK1-GRB-S (J3))
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Rys-Sikora, Krystyna E
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University of North Carolina Chapel Hill
Internal Medicine/Medicine
Schools of Medicine
Chapel Hill
United States
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Assimon, Magdalene M; Nguyen, Thuy; Katsanos, Suzanne L et al. (2016) Identification of volume overload hospitalizations among hemodialysis patients using administrative claims: a validation study. BMC Nephrol 17:173
Assimon, Magdalene M; Wenger, Julia B; Wang, Lily et al. (2016) Ultrafiltration Rate and Mortality in Maintenance Hemodialysis Patients. Am J Kidney Dis 68:911-922
Lebov, Jill F; Engel, Lawrence S; Richardson, David et al. (2016) Pesticide use and risk of end-stage renal disease among licensed pesticide applicators in the Agricultural Health Study. Occup Environ Med 73:3-12
Assimon, Magdalene M; Flythe, Jennifer E (2016) Variability May Be the ""Law of Life,"" but Blood Pressure Variability May Forebode a Shorter Life. Am J Kidney Dis 67:830-3
Flythe, Jennifer E; Assimon, Magdalene M; Wenger, Julia B et al. (2016) Ultrafiltration Rates and the Quality Incentive Program: Proposed Measure Definitions and Their Potential Dialysis Facility Implications. Clin J Am Soc Nephrol 11:1422-33
Lebov, Jill F; Engel, Lawrence S; Richardson, David et al. (2015) Pesticide exposure and end-stage renal disease risk among wives of pesticide applicators in the Agricultural Health Study. Environ Res 143:198-210
Matsuki, Kota; Hathaway, Catherine K; Chang, Albert S et al. (2015) Transforming growth factor beta1 and aldosterone. Curr Opin Nephrol Hypertens 24:139-44
Butler, Anne M; Kshirsagar, Abhijit V; Olshan, Andrew F et al. (2015) Trends in Anemia Management in Hemodialysis Patients with Cancer. Am J Nephrol 42:206-15
Lebov, Jill F; Valladares, Eliette; Peña, Rodolfo et al. (2015) A population-based study of prevalence and risk factors of chronic kidney disease in León, Nicaragua. Can J Kidney Health Dis 2:6
Assimon, Magdalene M; Flythe, Jennifer E (2015) Rapid ultrafiltration rates and outcomes among hemodialysis patients: re-examining the evidence base. Curr Opin Nephrol Hypertens 24:525-30

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