The objective of the U. of Michigan Training Program in Gastrointestinal Epidemiology is to develop academic gastroenterologists who are thoroughly trained in the design and execution of clinical/translational research. With this training, our trainees become junior faculty who successfully compete for external funding. In order to meet this objective, our program requires trainees to complete the following projects: (a) completion of a MSc in Clinical Research Design and Statistical Analysis at the U. of Michigan School of Public Health or completion of a MSc in Health Research through our Robert Wood Johsnon [sic] Clinical Scholars Program. Both programs provide formal training in research design, epidemiology and biostatistics;(b) completion of a comprehensive Gl Epidemiology series, which provides additional skills in grant writing, health care policy, and outcomes research methods;(c) design and execution of 3 clinical research projects (meta-analysis, retrospective database analysis, and prospective clinical trial) under the guidance of a team of research mentors;presentation of these research projects at national meetings and publication of these projects in peer-reviewed journals is also expected;(d) preparation and submission of a Career Development Award, which provides transitional funding for an independent career in academic medicine and research. Our program trains two post-doctoral trainees (i.e., gastroenterology fellows) per year. We request that our program be expanded to three trainees per year. The program is completed in two years. Three trainees have completed our program, and all trainees accepted tenure-track positions at academic medical centers and successfully applied for career development awards. This success partly reflects the numerous training resources at the U. of Michigan and the vast experience of our faculty in mentoring trainees, teaching research techniques and in guiding trainees through grant preparation. Relevance: Gl diseases impact the health of millions of Americans each year, producing direct and indirect costs of billions of dollars. Basic science is rapidly advancing our understanding of Gl disease, but application of these findings to patients requires patient-oriented research performed by skilled investigators trained in translational and clinical research.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Institutional National Research Service Award (T32)
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Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Densmore, Christine L
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University of Michigan Ann Arbor
Internal Medicine/Medicine
Schools of Medicine
Ann Arbor
United States
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Konerman, Monica A; Lok, Anna S (2015) Is it more cost-effective for patients with chronic hepatitis b to have a trial of interferon before considering Nucleos(t)ide analogue therapy? Clin Gastroenterol Hepatol 13:386-9
Mellinger, Jessica L; Richardson, Caroline R; Mathur, Amit K et al. (2015) Variation among United States hospitals in inpatient mortality for cirrhosis. Clin Gastroenterol Hepatol 13:577-84; quiz e30
Menees, Stacy B; Elliott, Eric; Govani, Shail et al. (2014) Adherence to recommended intervals for surveillance colonoscopy in average-risk patients with 1 to 2 small (<1 cm) polyps on screening colonoscopy. Gastrointest Endosc 79:551-7
Menees, Stacy B; Kim, H Myra; Wren, Patricia et al. (2014) Patient compliance and suboptimal bowel preparation with split-dose bowel regimen in average-risk screening colonoscopy. Gastrointest Endosc 79:811-820.e3
Konerman, Monica A; Mehta, Shruti H; Sutcliffe, Catherine G et al. (2014) Fibrosis progression in human immunodeficiency virus/hepatitis C virus coinfected adults: prospective analysis of 435 liver biopsy pairs. Hepatology 59:767-75
Konerman, M A; Yapali, S; Lok, A S (2014) Systematic review: identifying patients with chronic hepatitis C in need of early treatment and intensive monitoring--predictors and predictive models of disease progression. Aliment Pharmacol Ther 40:863-79
Konerman, Monica A; Lok, Anna S (2014) Diagnostic challenges of hepatitis C. JAMA 311:2536-7
Mellinger, Jessica L; Rossaro, Lorenzo; Naugler, Willscott E et al. (2014) Epstein-Barr virus (EBV) related acute liver failure: a case series from the US Acute Liver Failure Study Group. Dig Dis Sci 59:1630-7
DeBenedet, Anthony T; Scheiman, James M; Elta, Grace H et al. (2013) Peritoneal fluid bilirubin to serum bilirubin ratio for the diagnosis of bile leaks in orthotopic liver transplant recipients. Dig Dis Sci 58:3044-8
Mellinger, Jessica L; Volk, Michael L (2013) Multidisciplinary management of patients with cirrhosis: a need for care coordination. Clin Gastroenterol Hepatol 11:217-23

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