? Disorders of endocrinology and metabolism are prevalent in the U.S. Type 2 diabetes, previously found in middle aged and elderly adults, is now burgeoning in young adults and children. The onset of a disease that imparts high cardiovascular risk in ever-younger populations has staggering implications for public health. In addition, as the U.S. population ages, other disorders that increase cardiovascular risk (hypertension, dyslipidemia, obesity) and other common disorders of aging, such as osteoporosis, consume ever-larger proportions of health care expenditures. Addressing these difficult dilemmas requires not only the development of a critical mass of physicians to care for affected patients, but also the training of skilled researchers to develop innovative therapies and preventive measures and to delve into the basic mechanisms of diseases. The Indiana University School of Medicine is a leader in many fields of medicine. Its Section of Pediatric Endocrinology and Diabetes and the Division of Endocrinology and Metabolism in the Department of Medicine are both large well respected research divisions with a long history of mentoring pre- and postdoctoral trainees, including training one another's fellows in research that spans the spectrum of pediatric and adult endocrinology. The proposed Endocrine Scientist Training Program provides the opportunity for young scientists in Pediatric, Adult, or Combined Medicine-Pediatric Endocrinology training to enhance their skills in either basic laboratory, clinical, or translational research, leading to careers as independent academic researchers.-After completion of their residency training, highly qualified physicians will enter either the Internal Medicine, Pediatric Endocrinology, or combined Medicine-Pediatrics fellowship, receive clinical training in the respective discipline(s), then enter this combined program in one of two tracks, the Basic Science of Endocrinology Track or the Endocrinology Clinical Research Track. These tracks provide extensive direct and didactic research training. This program will train top-notch physician scientists in the field of Endocrinology who will engage in cutting-edge research to make major contributions to the health of the American people. With this resubmission, we have taken the opportunity to enhance the research training program. It provides a unique and innovative approach to training, and it puts the exceptional institutional resources now available to use, building on our history of success ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
1T32DK065549-01A1
Application #
6845197
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Hyde, James F
Project Start
2005-09-01
Project End
2010-06-30
Budget Start
2005-09-01
Budget End
2006-06-30
Support Year
1
Fiscal Year
2005
Total Cost
$119,664
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Pediatrics
Type
Schools of Medicine
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Chen, Melinda E; Chandramouli, Aaditya G; Considine, Robert V et al. (2018) Comparison of ?-Cell Function Between Overweight/Obese Adults and Adolescents Across the Spectrum of Glycemia. Diabetes Care 41:318-325
Hannon, Tamara S; Watson, Sara E; Jalou, Hasnaa E et al. (2018) Characteristics of Obstructive Sleep Apnea Across the Spectrum of Glucose Tolerance in Obese Adolescents. Front Endocrinol (Lausanne) 9:281
Hansen, David W; Nebesio, Todd D; DiMeglio, Linda A et al. (2018) Prevalence of Nephrocalcinosis in Pseudohypoparathyroidism: Is Screening Necessary? J Pediatr 199:263-266
Schoelwer, Melissa J; Donahue, Kelly L; Didrick, Paula et al. (2017) One-Year Follow-Up of Girls with Precocious Puberty and Their Mothers: Do Psychological Assessments Change over Time or with Treatment? Horm Res Paediatr 88:347-353
Chen, Melinda; Lash, Matthew; Nebesio, Todd et al. (2017) Change in BMI after radioactive iodine ablation for graves disease. Int J Pediatr Endocrinol 2017:5
Schoelwer, Melissa J; Tu, Wanzhu; Zhou, Junyi et al. (2017) TARGETED LEVOTHYROXINE THERAPY FOR TREATMENT OF CONGENITAL HYPOTHYROIDISM. Endocr Pract 23:1067-1071
Folsom, Lisal J; Slaven, James E; Nabhan, Zeina M et al. (2017) CHARACTERIZATION OF SPONTANEOUS AND INDUCED PUBERTY IN GIRLS WITH TURNER SYNDROME. Endocr Pract 23:768-774
Neyman, Anna; Eugster, Erica A (2017) Treatment of Girls and Boys with McCune-Albright Syndrome with Precocious Puberty - Update 2017. Pediatr Endocrinol Rev 15:136-141
Schoelwer, Melissa J; Viswanathan, Vidhya; Wilson, Amy et al. (2017) Infants With Congenital Adrenal Hyperplasia Are at Risk for Hypercalcemia, Hypercalciuria, and Nephrocalcinosis. J Endocr Soc 1:1160-1167
Folsom, Lisal J; Hannon, Tamara S (2017) Collaboration Is Key for Successful Treatment of Youth-Onset Type 2 Diabetes. J Adolesc Health 60:360-362

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