The primary objective of this ongoing program is to provide intensive basic and translational science training for individuals who will become outstanding vision researchers. Training is provided in the disciplines of immunology, cell biology, molecular biology, physiology, pharmacology, genetics, developmental biology, neuroscience and biochemistry, with an emphasis on understanding the fundamental mechanisms that underlie normal ocular processes, as well as corneal, retinal and choroidal diseases, cataract, glaucoma and visual processing. The program has a multidisciplinary approach, with emphasis on collaboration between basic scientists and the various clinical disciplines and it provides the facilities and supervision for laboratory investigations relative to some of the major missions of the National Eye Institute. The program directors oversee the selection of trainees and the provision of appropriate background, technical training and ongoing research supervision by the preceptors. The trainees include: (1) Predoctoral students from the Emory University Graduate School Division of Biological and Biomedical Sciences in the Programs of Biochemistry, Cell, and Developmental Biology, Neuroscience, Nutrition and Health Science, Immunology and Molecular Pathogenesis, and Molecular and Systems Pharmacology;(2) Postdoctoral Fellows seeking advanced training with one (or more) of the preceptors in a scientific area pertinent to vision research. Each trainee selects or is assigned a preceptor with whom he or she develops a research proposal, conducts the research and participates in the ongoing research projects of the preceptor. All trainees are required to participate in the seminar, course work, grand rounds and other educational activities of the Emory Eye Center, which is the focal point for eye research and clinical care in the region. Thus, the program also serves to integrate the clinical and basic science departments. In addition, the program successfully attracts minority trainees to careers in eye research, drawing on the outstanding resources of Atlanta academic and medical institutions.

Public Health Relevance

The future of curing blinding eye disease relies on a continued supply of well-trained vision scientists goal is to produce the next generation of scientists who are well versed in the basic, clinical, and translational research approaches that will be needed to fulfill the mission of the National Eye Institute.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Institutional National Research Service Award (T32)
Project #
5T32EY007092-25
Application #
8011035
Study Section
Special Emphasis Panel (ZEY1-VSN (10))
Program Officer
Agarwal, Neeraj
Project Start
1984-09-28
Project End
2014-12-31
Budget Start
2011-01-01
Budget End
2011-12-31
Support Year
25
Fiscal Year
2011
Total Cost
$189,690
Indirect Cost
Name
Emory University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Chiang, Bryce; Kim, Yoo Chun; Edelhauser, Henry F et al. (2016) Circumferential flow of particles in the suprachoroidal space is impeded by the posterior ciliary arteries. Exp Eye Res 145:424-31
Chiang, Bryce; Venugopal, Nitin; Edelhauser, Henry F et al. (2016) Distribution of particles, small molecules and polymeric formulation excipients in the suprachoroidal space after microneedle injection. Exp Eye Res 153:101-109
Bergen, Michael A; Park, Han Na; Chakraborty, Ranjay et al. (2016) Altered Refractive Development in Mice With Reduced Levels of Retinal Dopamine. Invest Ophthalmol Vis Sci 57:4412-4419
Mariani, Laura E; Bijlsma, Maarten F; Ivanova, Anna I et al. (2016) Arl13b regulates Shh signaling from both inside and outside the cilium. Mol Biol Cell :
Markand, Shanu; Baskin, Natecia L; Chakraborty, Ranjay et al. (2016) IRBP deficiency permits precocious ocular development and myopia. Mol Vis 22:1291-1308
Chiang, B; Kim, Y C; Doty, A C et al. (2016) Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma. J Control Release 228:48-57
Struebing, Felix L; Lee, Richard K; Williams, Robert W et al. (2016) Genetic Networks in Mouse Retinal Ganglion Cells. Front Genet 7:169
Persichetti, Andrew S; Dilks, Daniel D (2016) Perceived egocentric distance sensitivity and invariance across scene-selective cortex. Cortex 77:155-63
Hwang, Christopher K; Hubbard, G Baker; Hutchinson, Amy K et al. (2015) Outcomes after Intravitreal Bevacizumab versus Laser Photocoagulation for Retinopathy of Prematurity: A 5-Year Retrospective Analysis. Ophthalmology 122:1008-15
Allen, Rachael S; Olsen, Timothy W; Sayeed, Iqbal et al. (2015) Progesterone treatment in two rat models of ocular ischemia. Invest Ophthalmol Vis Sci 56:2880-91

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