Nineteen neuroscientists within Harvard's Neuroscience Program request continued funding for four pre-doctoral positions in our Training Program in Visual Neuroscience. Training focuses on the study of visual pathways from retina to brain, and of the cellular, molecular and developmental neurobiology of the visual system. These faculty members are distributed throughout the university. Ten faculty members are in basic science departments at the Medical School, six are in hospital-based laboratories, and three are in the Faculty of Arts and Sciences. Over the past two decades, Harvard University has greatly expanded the number faculty members who study the molecular, developmental, and neural-systems approaches to visual science. Students can choose laboratories among a large community of vision researchers, most of who are affiliated with Harvard's NEI Core Grant in Vision research. The goal of the Visual Neuroscience Training Program is to build a large, coherent group of students based in this Harvard-wide vision community, who are trained by its faculty and who have a strong sense of community. The grant will support two students in their second year and two in their third, but students remain actively involved with the program as they advance to later years, creating a large cohort of affiliated students. We train and supervise these students with courses, thesis committees, seminars, symposia, and our "Systems-Vision" journal club. Thus, trainees interact with the faculty and with each other throughout their graduate careers. Many vision scientists visit Harvard every year to give seminars;trainees at all levels interact with them over lunch and in lab visits. Through these activities, we will help train a new generation of vision scientists whose scientific careers will help us understand all aspects of the visual system: development, information processing, and disease.

Public Health Relevance

The laboratories of the Training Grant faculty study the development and function of the eye and the parts of the brain that serve vision. These laboratories do research on topics that are important for understanding a range of visual disorders, including blindness, strabismus, amblyopia, and dyslexia. Training students to do research in visual neuroscience is essential to ensure progress on understanding, treating and ultimately curing visual disorders.

Agency
National Institute of Health (NIH)
Type
Institutional National Research Service Award (T32)
Project #
2T32EY007110-26
Application #
8664195
Study Section
Special Emphasis Panel (ZEY1)
Program Officer
Agarwal, Neeraj
Project Start
Project End
Budget Start
Budget End
Support Year
26
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Harvard Medical School
Department
Biology
Type
Schools of Medicine
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02115
Gómez-Laberge, Camille; Smolyanskaya, Alexandra; Nassi, Jonathan J et al. (2016) Bottom-Up and Top-Down Input Augment the Variability of Cortical Neurons. Neuron 91:540-7
Born, Richard T; Trott, Alexander R; Hartmann, Till S (2015) Cortical magnification plus cortical plasticity equals vision? Vision Res 111:161-9
Kostadinov, Dimitar; Sanes, Joshua R (2015) Protocadherin-dependent dendritic self-avoidance regulates neural connectivity and circuit function. Elife 4:
Hauser, Jessica L; Liu, Xiaojin; Litvina, Elizabeth Y et al. (2014) Prolonged synaptic currents increase relay neuron firing at the developing retinogeniculate synapse. J Neurophysiol 112:1714-28
Fitzgerald, Jamie K; Freedman, David J; Fanini, Alessandra et al. (2013) Biased associative representations in parietal cortex. Neuron 77:180-91
Hauser, Jessica L; Edson, Eleanore B; Hooks, Bryan M et al. (2013) Metabotropic glutamate receptors and glutamate transporters shape transmission at the developing retinogeniculate synapse. J Neurophysiol 109:113-23
Histed, Mark H; Ni, Amy M; Maunsell, John H R (2013) Insights into cortical mechanisms of behavior from microstimulation experiments. Prog Neurobiol 103:115-30
Hull, Court A; Chu, YunXiang; Thanawala, Monica et al. (2013) Hyperpolarization induces a long-term increase in the spontaneous firing rate of cerebellar Golgi cells. J Neurosci 33:5895-902
Lefebvre, Julie L; Kostadinov, Dimitar; Chen, Weisheng V et al. (2012) Protocadherins mediate dendritic self-avoidance in the mammalian nervous system. Nature 488:517-21
Fitzgerald, Jamie K; Swaminathan, Sruthi K; Freedman, David J (2012) Visual categorization and the parietal cortex. Front Integr Neurosci 6:18

Showing the most recent 10 out of 40 publications