The aim of this program is to educate well-trained scholars with an advanced appreciation of genetic rationales and methods to 1) perform basic and applied biomedical research, 2) provide future educators in this discipline, and 3) fulfill health- related positions, both academic and in industry, requiring a sophisticated understanding of genetics and genomics. The training faculty is comprised of fifty-five distinguished and respected members of the scientific community. Their specific strengths are focused in the areas of: chromosome organization and behavior, gene expression and developmental genetics, genetics of model organisms, population and evolutionary genetics, systems biology, and the genetics of human diseases with special emphasis on genetic alterations in cancer, diabetes, cardiac disorders and asthma. Diverse systems including viruses, bacteria, Arabidopsis, yeast, ciliates, Drosophila, nematodes, zebrafish, mice, humans, and a variety of other plant and animal species. Research is also characterized by the use of interdisciplinary approaches.
The aim of this program is to educate well-trained scholars with an advanced appreciation of genetic rationales and methods to 1) perform basic and applied biomedical research, 2) provide future educators in this discipline, and 3) fulfill health- related positions, both academic and in industry, requiring a sophisticated understanding of genetics and genomics.
|Parker, Clarissa C; Gopalakrishnan, Shyam; Carbonetto, Peter et al. (2016) Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice. Nat Genet 48:919-26|
|Burrows, Courtney K; Banovich, Nicholas E; Pavlovic, Bryan J et al. (2016) Genetic Variation, Not Cell Type of Origin, Underlies the Majority of Identifiable Regulatory Differences in iPSCs. PLoS Genet 12:e1005793|
|Semlow, Daniel R; Blanco, Mario R; Walter, Nils G et al. (2016) Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites. Cell 164:985-98|
|Kariuki, Silvia N; Blischak, John D; Nakagome, Shigeki et al. (2016) Patterns of Transcriptional Response to 1,25-Dihydroxyvitamin D3 and Bacterial Lipopolysaccharide in Primary Human Monocytes. G3 (Bethesda) 6:1345-55|
|Stepien, Courtney C; Pfister, Catherine A; Wootton, J Timothy (2016) Functional Traits for Carbon Access in Macrophytes. PLoS One 11:e0159062|
|MacQueen, Alice; Bergelson, Joy (2016) Modulation of R-gene expression across environments. J Exp Bot 67:2093-105|
|Morris, Geoffrey P; Hu, Zhenbin; Grabowski, Paul P et al. (2016) Genotypic diversity effects on biomass production in native perennial bioenergy cropping systems. Glob Change Biol Bioenergy 8:1000-1014|
|Mika, Katelyn M; Lynch, Vincent J (2016) An Ancient Fecundability-Associated Polymorphism Switches a Repressor into an Enhancer of Endometrial TAP2 Expression. Am J Hum Genet 99:1059-1071|
|Hoi, Charlene S L; Xiong, Wenjun; Rebay, Ilaria (2016) Retinal Axon Guidance Requires Integration of Eya and the Jak/Stat Pathway into Phosphotyrosine-Based Signaling Circuitries in Drosophila. Genetics 203:1283-95|
|Blischak, John D; Davenport, Emily R; Wilson, Greg (2016) A Quick Introduction to Version Control with Git and GitHub. PLoS Comput Biol 12:e1004668|
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