The Molecular Biosciences Training Grant (MBTG) Program at the University of Wisconsin-Madison supports and enhances the training of predoctoral students who aspire to become research leaders in the cellular, biochemical, and molecular sciences. The MBTG Program has selected a strong cadre of 94 nationally recognized trainers from 26 different departments to mentor trainees. Trainees are selected each year from an outstanding pool of over 500 training grant-eligible applicants to top-ranked campus Ph.D. programs, including the Integrated Program in Biochemistry, Cellular and Molecular Biology, and Microbiology. The MBTG Program provides trainees with early and intensive orientation and advising, expanded lab rotation opportunities, and support for intellectual and professional development. Interdisciplinary training is promoted by a broad core curriculum and a weekly seminar series. The MBTG Program also provides instruction in appropriate scientific conduct, progress tracking, and career advising. In its 35 year history, the MBTG Program has enhanced the training of well over 500 graduate students, many of whom have become leaders in academia, industry and government laboratories, and non-profit organizations. We currently have 62 trainees, 34 of whom are supported on training grant funds at any one time. The MBTG Program is directed by a dedicated Steering Committee consisting of six trainers, two trainees, and a program administrator. The Ph.D. programs that contribute students to the MBTG Program receive substantial support from the university in the form of recruiting funds and fellowships for underrepresented minority candidates. The UW campus continually improves our state-of-the-art facilities for biosciences research, which directly benefits MBTG trainees and trainers. This effort assures UW-Madison's continued eminence in biomedical research. To capitalize on the expanding research infrastructure and trainer pool, we request a gradual increase of funded positions from the current 34 to 40 by the year 2015.

Public Health Relevance

The enormous potential of biomedical research to improve the quality of life and reduce the cost of healthcare for the people of this and other countries can only be realized by increasing the quality, diversity and size of the pool of trained researchers, which is the direct goal of the MBTG Program.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Gindhart, Joseph G
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Wisconsin Madison
Schools of Medicine
United States
Zip Code
Mead, Matthew E; Stanton, Brynne C; Kruzel, Emilia K et al. (2015) Targets of the Sex Inducer homeodomain proteins are required for fungal development and virulence in Cryptococcus neoformans. Mol Microbiol 95:804-18
Lowe, Tiffany M; Ailloud, Florent; Allen, Caitilyn (2015) Hydroxycinnamic Acid Degradation, a Broadly Conserved Trait, Protects Ralstonia solanacearum from Chemical Plant Defenses and Contributes to Root Colonization and Virulence. Mol Plant Microbe Interact 28:286-97
Bhattacharyya, Basudeb; Keck, James L (2014) Grip it and rip it: structural mechanisms of DNA helicase substrate binding and unwinding. Protein Sci 23:1498-507
Rodrigues, Rachel B; Sabat, Gregorz; Minkoff, Benjamin B et al. (2014) Expression of a translationally fused TAP-tagged plasma membrane proton pump in Arabidopsis thaliana. Biochemistry 53:566-78
Ramsey, Meghan E; Hackett, Kathleen T; Bender, Tobias et al. (2014) TraK and TraB are conserved outer membrane proteins of the Neisseria gonorrhoeae Type IV secretion system and are expressed at low levels in wild-type cells. J Bacteriol 196:2954-68
Banta, Amy B; Cuff, Marianne E; Lin, Hueylie et al. (2014) Structure of the RNA polymerase assembly factor Crl and identification of its interaction surface with sigma S. J Bacteriol 196:3279-88
Petty, Ryan V; Basta, Holly A; Bacot-Davis, Valjean R et al. (2014) Binding interactions between the encephalomyocarditis virus leader and protein 2A. J Virol 88:13503-9
Ronayne, Erin A; Cox, Michael M (2014) RecA-dependent programmable endonuclease Ref cleaves DNA in two distinct steps. Nucleic Acids Res 42:3871-83
Neal, Lori M; Knoll, Laura J (2014) Toxoplasma gondii profilin promotes recruitment of Ly6Chi CCR2+ inflammatory monocytes that can confer resistance to bacterial infection. PLoS Pathog 10:e1004203
Singh, Swati; Reese, Jordan M; Casanova-Torres, Angel M et al. (2014) Microbial population dynamics in the hemolymph of Manduca sexta infected with Xenorhabdus nematophila and the entomopathogenic nematode Steinernema carpocapsae. Appl Environ Microbiol 80:4277-85

Showing the most recent 10 out of 457 publications