The Molecular Biosciences Training Grant (MBTG) Program at the University of Wisconsin-Madison supports and enhances the training of predoctoral students who aspire to become research leaders in the cellular, biochemical, and molecular sciences. The MBTG Program has selected a strong cadre of 94 nationally recognized trainers from 26 different departments to mentor trainees. Trainees are selected each year from an outstanding pool of over 500 training grant-eligible applicants to top-ranked campus Ph.D. programs, including the Integrated Program in Biochemistry, Cellular and Molecular Biology, and Microbiology. The MBTG Program provides trainees with early and intensive orientation and advising, expanded lab rotation opportunities, and support for intellectual and professional development. Interdisciplinary training is promoted by a broad core curriculum and a weekly seminar series. The MBTG Program also provides instruction in appropriate scientific conduct, progress tracking, and career advising. In its 35 year history, the MBTG Program has enhanced the training of well over 500 graduate students, many of whom have become leaders in academia, industry and government laboratories, and non-profit organizations. We currently have 62 trainees, 34 of whom are supported on training grant funds at any one time. The MBTG Program is directed by a dedicated Steering Committee consisting of six trainers, two trainees, and a program administrator. The Ph.D. programs that contribute students to the MBTG Program receive substantial support from the university in the form of recruiting funds and fellowships for underrepresented minority candidates. The UW campus continually improves our state-of-the-art facilities for biosciences research, which directly benefits MBTG trainees and trainers. This effort assures UW-Madison's continued eminence in biomedical research. To capitalize on the expanding research infrastructure and trainer pool, we request a gradual increase of funded positions from the current 34 to 40 by the year 2015.

Public Health Relevance

The enormous potential of biomedical research to improve the quality of life and reduce the cost of healthcare for the people of this and other countries can only be realized by increasing the quality, diversity and size of the pool of trained researchers, which is the direct goal of the MBTG Program.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Gindhart, Joseph G
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Wisconsin Madison
Schools of Medicine
United States
Zip Code
Book, Adam J; Lewin, Gina R; McDonald, Bradon R et al. (2016) Evolution of High Cellulolytic Activity in Symbiotic Streptomyces through Selection of Expanded Gene Content and Coordinated Gene Expression. PLoS Biol 14:e1002475
Catlett, Timothy S; Gomez, Timothy M (2016) Division of labor in the growth cone by DSCR1. J Cell Biol 213:407-9
Frankel, E B; Audhya, Anjon (2016) Burning cellular bridges: Two pathways to the big breakup. J Cell Biol 212:491-3
Caine, Elizabeth A; Moncla, Louise H; Ronderos, Monica D et al. (2016) A Single Mutation in the VP1 of Enterovirus 71 Is Responsible for Increased Virulence and Neurotropism in Adult Interferon-Deficient Mice. J Virol 90:8592-604
Spraker, Joseph E; Sanchez, Laura M; Lowe, Tiffany M et al. (2016) Ralstonia solanacearum lipopeptide induces chlamydospore development in fungi and facilitates bacterial entry into fungal tissues. ISME J 10:2317-30
Perlenfein, Tyler J; Murphy, Regina M (2016) Expression, purification, and characterization of human cystatin C monomers and oligomers. Protein Expr Purif 117:35-43
Moussavi-Harami, S F; Mladinich, K M; Sackmann, E K et al. (2016) Microfluidic device for simultaneous analysis of neutrophil extracellular traps and production of reactive oxygen species. Integr Biol (Camb) 8:243-52
Dinis, Jorge M; Florek, Nicholas W; Fatola, Omolayo O et al. (2016) Deep Sequencing Reveals Potential Antigenic Variants at Low Frequencies in Influenza A Virus-Infected Humans. J Virol 90:3355-65
Wahl-Jensen, Victoria; Johnson, Joshua C; Lauck, Michael et al. (2016) Divergent Simian Arteriviruses Cause Simian Hemorrhagic Fever of Differing Severities in Macaques. MBio 7:e02009-15
Winkelman, Jared T; Chandrangsu, Pete; Ross, Wilma et al. (2016) Open complex scrunching before nucleotide addition accounts for the unusual transcription start site of E. coli ribosomal RNA promoters. Proc Natl Acad Sci U S A 113:E1787-95

Showing the most recent 10 out of 616 publications