This application seeks continued support for training of predoctoral students in genetics and development at Cornell University. The goal of the program is to produce highly skilled and knowledgeable scientists who will make significant contributions to biomedical research and education. In the program, students are provided research training in the framework of dissertation research carried out under the supervision of a faculty mentor and overseen by a committee of faculty. The 39 participating faculty represent four areas of strength: Evolutionary Genetics, Genetic Analysis of Cell Biology, Development, and Molecular Genetics. Faculty members in each area have extensive training experience and have active and productive laboratories with state-of-the-art equipment and facilities. The program also has a significant academic component that includes training in quantitative skills, presentation skills, and critical evaluation of the primary literature. A selection of courses provides a broad theoretical background appropriate for the students'research. Students also participate in journal clubs, attend seminars by visiting scientists, and present seminars on their own and others'research. The program has mechanisms for monitoring student progress that include a qualifying exam, yearly committee meetings, yearly progress reports, and yearly evaluations by the training faculty as a whole. Currently there are 56 predoctoral students training in the graduate program and we are seeking support for nine trainees.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007617-30
Application #
8100519
Study Section
Special Emphasis Panel (ZGM1-BRT-5 (CG))
Program Officer
Poodry, Clifton A
Project Start
1979-07-01
Project End
2012-06-30
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
30
Fiscal Year
2011
Total Cost
$362,992
Indirect Cost
Name
Cornell University
Department
Biochemistry
Type
Schools of Earth Sciences/Natur
DUNS #
872612445
City
Ithaca
State
NY
Country
United States
Zip Code
14850
Salerno Jr, Stephen; Mehrmohamadi, Mahya; Liberti, Maria V et al. (2017) RRmix: A method for simultaneous batch effect correction and analysis of metabolomics data in the absence of internal standards. PLoS One 12:e0179530
Cui, Jun; Lai, Yun Wei; Sartain, Caroline V et al. (2016) The Drosophila prage Gene, Required for Maternal Transcript Destabilization in Embryos, Encodes a Predicted RNA Exonuclease. G3 (Bethesda) 6:1687-93
Ser, Zheng; Gao, Xia; Johnson, Christelle et al. (2016) Targeting One Carbon Metabolism with an Antimetabolite Disrupts Pyrimidine Homeostasis and Induces Nucleotide Overflow. Cell Rep 15:2367-76
Wagoner, Jessica A; Sun, Tao; Lin, Lin et al. (2015) Cytidine deaminase motifs within the DYW domain of two pentatricopeptide repeat-containing proteins are required for site-specific chloroplast RNA editing. J Biol Chem 290:2957-68
Modzelewski, Andrew J; Hilz, Stephanie; Crate, Elizabeth A et al. (2015) Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males. J Cell Sci 128:2314-27
Flores, Heather A; DuMont, Vanessa L Bauer; Fatoo, Aalya et al. (2015) Adaptive evolution of genes involved in the regulation of germline stem cells in Drosophila melanogaster and D. simulans. G3 (Bethesda) 5:583-92
Kaneuch, Taro; Wolfner, Mariana F; Aigaki, Toshiro (2015) A calcium rise occurs as activating Drosophila eggs move through the female reproductive tract. Mol Reprod Dev 82:501
Blekhman, Ran; Goodrich, Julia K; Huang, Katherine et al. (2015) Host genetic variation impacts microbiome composition across human body sites. Genome Biol 16:191
Barrios, Clara; Beaumont, Michelle; Pallister, Tess et al. (2015) Gut-Microbiota-Metabolite Axis in Early Renal Function Decline. PLoS One 10:e0134311
Kaneuchi, Taro; Sartain, Caroline V; Takeo, Satomi et al. (2015) Calcium waves occur as Drosophila oocytes activate. Proc Natl Acad Sci U S A 112:791-6

Showing the most recent 10 out of 77 publications