The objective of this application is the training of 13 pre-doctoral students per year over the next five years in the interdisciplinary area of molecular biophysics. Trainees will be selected competitively from a pool of approximately 75 graduate students in eight departments of the University of Washington (Biochemistry, Bioengineering, Biological Structure, Chemistry, Immunology, Medicinal Chemistry, Physiology and Biophysics, and Physics) and the Fred Hutchinson Cancer Research Center. The trainees will be exposed to modern molecular biophysics through a series of interdisciplinary courses and seminars and through specialized thesis research. ? ?
| Rusnac, Domni?a-Valeria; Lin, Hsiu-Chuan; Canzani, Daniele et al. (2018) Recognition of the Diglycine C-End Degron by CRL2KLHDC2 Ubiquitin Ligase. Mol Cell 72:813-822.e4 |
| Dingens, Adam S; Acharya, Priyamvada; Haddox, Hugh K et al. (2018) Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV. PLoS Pathog 14:e1007159 |
| Cornell, Caitlin E; Skinkle, Allison D; He, Shushan et al. (2018) Tuning Length Scales of Small Domains in Cell-Derived Membranes and Synthetic Model Membranes. Biophys J 115:690-701 |
| Borst, Andrew J; Weidle, Connor E; Gray, Matthew D et al. (2018) Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core. Elife 7: |
| Leonen, Calvin Jon Antolin; Upadhyay, Esha; Chatterjee, Champak (2018) Studies of biochemical crosstalk in chromatin with semisynthetic histones. Curr Opin Chem Biol 45:27-34 |
| Hsu, Peter L; Li, Heng; Lau, Ho-Tak et al. (2018) Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module. Cell 174:1106-1116.e9 |
| Baughman, Hannah E R; Clouser, Amanda F; Klevit, Rachel E et al. (2018) HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation. J Biol Chem 293:2687-2700 |
| Rayermann, Scott P; Rayermann, Glennis E; Cornell, Caitlin E et al. (2017) Hallmarks of Reversible Separation of Living, Unperturbed Cell Membranes into Two Liquid Phases. Biophys J 113:2425-2432 |
| James, Zachary M; Borst, Andrew J; Haitin, Yoni et al. (2017) CryoEM structure of a prokaryotic cyclic nucleotide-gated ion channel. Proc Natl Acad Sci U S A 114:4430-4435 |
| Frenz, Brandon; Walls, Alexandra C; Egelman, Edward H et al. (2017) RosettaES: a sampling strategy enabling automated interpretation of difficult cryo-EM maps. Nat Methods 14:797-800 |
Showing the most recent 10 out of 165 publications
