This application is for renewal of the Biotechnology Training Program at Washington State University (WSU) that has been continuously funded since 1989. During our current award period the Program has continued to gain in importance and recognition, both at the local WSU level and beyond. The success of the Program is based on many factors, one of which has been the continuous and generous support provided by both our University and by the State of Washington. For this renewal the University has not only pledged to continue its support but to significantly increase its level of contribution. A major factor that has led to these University and State commitments is the fact that, over the years, the Training Faculty has continuously strived to refine and improve the quality of the Program and its offerings in order to meet the ever-changing needs of the biotechnology sector and provide the best possible education for our Trainees. As we enter our twentieth year of operation, greater than ever interest and support for the Program is evident among the Trainees, the Training Faculty and the University, providing clear evidence of our success in developing a robust and thriving training program. On this basis we enthusiastically apply for renewal of funding for 10 Trainee positions/year for the next five years.
The biotechnology industry in the United States has now surpassed pharmaceutical companies as the primary source of new drugs and medicines for the fourth straight year. Furthermore, biotechnology is designated as a high growth industry by the U.S. Department of Labor which projects double digit annual increases in the number of professional and technical jobs in this area through 2012 and beyond. Our Training Program is designed to address these current and future needs by providing interdisciplinary graduate training in biotechnology with a major emphasis on the fundamentals and complexities of protein biochemistry and its derivative science, proteomics.
|Johnston, Gunner P; Contreras, Erik M; Dabundo, Jeffrey et al. (2017) Cytoplasmic Motifs in the Nipah Virus Fusion Protein Modulate Virus Particle Assembly and Egress. J Virol 91:|
|Gray, Kevin T; Kostyukova, Alla S; Fath, Thomas (2017) Actin regulation by tropomodulin and tropomyosin in neuronal morphogenesis and function. Mol Cell Neurosci 84:48-57|
|Weed, Darin J; Pritchard, Suzanne M; Gonzalez, Floricel et al. (2017) Mildly Acidic pH Triggers an Irreversible Conformational Change in the Fusion Domain of Herpes Simplex Virus 1 Glycoprotein B and Inactivation of Viral Entry. J Virol 91:|
|Moroz, Natalia; Fritch, Karen R; Marcec, Matthew J et al. (2017) Extracellular Alkalinization as a Defense Response in Potato Cells. Front Plant Sci 8:32|
|Dinkel, Kelcey D; Schneider, David A; Muñoz-Gutiérrez, Juan F et al. (2017) Correlation of cellular factors and differential scrapie prion permissiveness in ovine microglia. Virus Res 240:69-80|
|Schaeffer, Scott M; Christian, Ryan; Castro-Velasquez, Nohely et al. (2017) Comparative ultrastructure of fruit plastids in three genetically diverse genotypes of apple (Malus × domestica Borkh.) during development. Plant Cell Rep 36:1627-1640|
|Colpan, Mert; Ly, Thu; Grover, Samantha et al. (2017) The cardiomyopathy-associated K15N mutation in tropomyosin alters actin filament pointed end dynamics. Arch Biochem Biophys 630:18-26|
|Mobberley, Jennifer M; Lindemann, Stephen R; Bernstein, Hans C et al. (2017) Organismal and spatial partitioning of energy and macronutrient transformations within a hypersaline mat. FEMS Microbiol Ecol 93:|
|Ogden, Aaron J; Gargouri, Mahmoud; Park, JeongJin et al. (2017) Integrated analysis of zone-specific protein and metabolite profiles within nitrogen-fixing Medicago truncatula-Sinorhizobium medicae nodules. PLoS One 12:e0180894|
|Gall, Cory A; Scoles, Glen A; Magori, Krisztian et al. (2017) Laboratory colonization stabilizes the naturally dynamic microbiome composition of field collected Dermacentor andersoni ticks. Microbiome 5:133|
Showing the most recent 10 out of 284 publications