The focus of the Medical Scientist Training Program (MSTP) at the University of Alabama at Birmingham (UAB) is to train outstanding young people in the intellectual discipline of being a scientific investigator and a thoroughly trained physicia. Although the ultimate career pathway for individual trainees may range from the conduct of basic biomedical research to clinical trials of novel therapeutic agents or procedures, the net effect of this cadre of investigators will be to increase the translation of basic biomedical understanding into clinical practice. Our Program aims to 1) offer superb classroom training in both basic science education and the fundamentals of clinical education; 2) train students in the tools necessary to become successful biomedical scientists, including grant and manuscript writing, as well as time and laboratory management; 3) help students obtain the competencies to become excellent physicians, including clinical skills, medical knowledge, practice-based learning, interpersonal communication, professionalism, and evidence-based medicine; and 4) graduate physician-scientists who go on to become leaders in academic medical centers throughout the country. The basic structure of the MSTP curriculum at UAB is similar to most programs with three distinct phases - two years of basic science course work and laboratory rotations in the summers (Pre-clinical Phase), an extended period of laboratory research leading to the PhD (Research Phase), followed by a clinical training leading to the MD degree (Clinical Phase). One key difference in our program is that students take both graduate school coursework and medical school coursework during their first two years and integrate a continuing clinical education experience into their graduate years. Our MSTP students can choose to do their PhD in either multiple theme-based programs; which include cancer biology, pathobiology, immunology, microbiology, neuroscience, genetics, biochemistry, and cell, developmental, and molecular biology or in departmental-based programs; which include biomedical engineering, nutrition, and public health. The average time to complete our program is 7.7 years. The program usually accepts 8 students each year and currently has a total student body of 61 active students.

Public Health Relevance

The rapid advances in biomedical sciences of the past 30 years has resulted in a critical need for well trained investigators who also have direct involvement with clinical Medicine to translate the multiple new discoveries in biomedical science into workable clinical applications. Joint MD/PhD training of the most outstanding individuals in both modern medicine and the special intellectual perspective and technical know-how of basic biomedical science is a key component of meeting this need.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
3T32GM008361-25S1
Application #
9306463
Study Section
Special Emphasis Panel (ZGM1)
Program Officer
Preusch, Peter
Project Start
1992-07-01
Project End
2020-06-30
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
25
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Pathology
Type
Schools of Medicine
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Roberts, Brian S; Hardigan, Andrew A; Moore, Dianna E et al. (2018) Discovery and Validation of Circulating Biomarkers of Colorectal Adenoma by High-Depth Small RNA Sequencing. Clin Cancer Res 24:2092-2099
Whitley, Sarah K; Balasubramani, Anand; Zindl, Carlene L et al. (2018) IL-1R signaling promotes STAT3 and NF-?B factor recruitment to distal cis-regulatory elements that regulate Il17a/f transcription. J Biol Chem 293:15790-15800
Lever, Jeremie M; Yang, Zhengqin; Boddu, Ravindra et al. (2018) Parabiosis reveals leukocyte dynamics in the kidney. Lab Invest 98:391-402
Webb, William M (2018) Rationalism, Empiricism, and Evidence-Based Medicine: A Call for a New Galenic Synthesis. Medicines (Basel) 5:
Ma, Elizabeth; Fu, Yuchang; Garvey, W Timothy (2018) Relationship of Circulating miRNAs with Insulin Sensitivity and Associated Metabolic Risk Factors in Humans. Metab Syndr Relat Disord 16:82-89
DiToro, Daniel; Winstead, Colleen J; Pham, Duy et al. (2018) Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells. Science 361:
Bandari, Shyam K; Purushothaman, Anurag; Ramani, Vishnu C et al. (2018) Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior. Matrix Biol 65:104-118
Souder, J Paige; Gorelick, Daniel A (2018) Assaying uptake of endocrine disruptor compounds in zebrafish embryos and larvae. Comp Biochem Physiol C Toxicol Pharmacol 208:105-113
Dussaq, Alex M; Kennell Jr, Timothy; Eustace, Nicholas J et al. (2018) Kinomics toolbox-A web platform for analysis and viewing of kinomic peptide array data. PLoS One 13:e0202139
Ramaker, Ryne C; Gordon, Emily R; Cooper, Sara J (2018) R2DGC: threshold-free peak alignment and identification for 2D gas chromatography-mass spectrometry in R. Bioinformatics 34:1789-1791

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