This proposal is for the second competitive renewal of the training grant, """"""""Predoctoral Training of Neuroscientists"""""""", 5T32-GM08471, at the University of Minnesota. Trainees in this program are pursuing a Ph.D. through the Graduate Program in Neuroscience. Our understanding of the nervous system is expanding at an unparalleled pace. The challenge ahead is to train neuroscientists who possess the diverse knowledge and research skills required by this highly multidisciplinary field. The proposed training program funds predoctoral students primarily during their first year in the Graduate Program in Neuroscience. The program is built around a core of didactic coursework in neuroscience, dissertation research, and exposure to neuroscience on the national level. Flexibility and time for in-depth development of collateral fields of knowledge and research skills are provided. Several unique educational opportunities are available and time and attention are given to the students' professional development. A group of 64 trainers is proposed that reflects the diversity of the areas of study and research techniques in neuroscience. Research interests range from the cell and molecular to the systems and behavioral levels. Each trainer directs a productive research program and has demonstrated commitment to teaching and training. Representing 9 colleges and 21 departments throughout the University, the trainers are united by their participation in the Graduate Program in Neuroscience. An impressive array of individual trainer resources and institutional resources is available to the trainees. The Graduate Program in Neuroscience has a 10-year track record of attracting excellent students into this training grant. The trainees will be provided a strong, broad foundation in neuroscience to meet not only the immediate goal of completing a doctoral thesis, but the more important, long term goal of becoming independent, productive researchers.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008471-15
Application #
7253097
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Cole, Alison E
Project Start
1993-07-01
Project End
2008-06-30
Budget Start
2007-07-01
Budget End
2008-06-30
Support Year
15
Fiscal Year
2007
Total Cost
$275,142
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Neurosciences
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Sweis, Brian M; Abram, Samantha V; Schmidt, Brandy J et al. (2018) Sensitivity to ""sunk costs"" in mice, rats, and humans. Science 361:178-181
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Tonn Eisinger, Katherine R; Larson, Erin B; Boulware, Marissa I et al. (2018) Membrane estrogen receptor signaling impacts the reward circuitry of the female brain to influence motivated behaviors. Steroids 133:53-59
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Sweis, Brian M; Larson, Erin B; Redish, A David et al. (2018) Altering gain of the infralimbic-to-accumbens shell circuit alters economically dissociable decision-making algorithms. Proc Natl Acad Sci U S A 115:E6347-E6355
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Satrom, Katherine M; Ennis, Kathleen; Sweis, Brian M et al. (2018) Neonatal hyperglycemia induces CXCL10/CXCR3 signaling and microglial activation and impairs long-term synaptogenesis in the hippocampus and alters behavior in rats. J Neuroinflammation 15:82
Nippert, Amy R; Biesecker, Kyle R; Newman, Eric A (2018) Mechanisms Mediating Functional Hyperemia in the Brain. Neuroscientist 24:73-83

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