The UCSF Graduate Program in Biomedical sciences is an interdisciplinary PhD program that trains students for research careers investigating the molecular basis of tissue and organ function in human health and disease. It offers an integrative curriculum, designed specifically for graduate students, which provides a foundation in cell biology, molecular biology and genetics as applied to research problems in metazoan development, physiology and disease. It provides opportunities for deep exposure to focus areas and intensive mentoring through small group discussion-style courses and technology workshops, as well as translational courses that incorporate discussion of patient cases. Training is supported by laboratory rotations, journal clubs and research seminars. The program's mentoring faculty consists of 120 members drawn from both basic science and clinical departments. Their research interests are broad, but organized into eight thematic areas: Cancer Biology and Cell Signaling, Human Genetics, Vascular and Cardiac Biology, Developmental and Stem Cell Biology, Immunology, Microbial Pathogenesis and Virology, Neuroscience, and Tissue/Organ Biology and Endocrinology. Trainees are chosen from a national applicant pool, with special effort to include underrepresented minorities. The interdisciplinary spirit of the program reflects the interactive scientific culture at UCSF.

Public Health Relevance

The goal of predoctoral training in the Biomedical Sciences at UCSF is to provide a world-class education for the next generation of researchers in the field, equipping them to make fundamental discoveries about mechanisms underlying normal human physiology and disease. Trainees go on to have highly successful careers in academia and the biotechnology industry. Human health and society-at-large will benefit directly as our training program produces creative, highly trained scientists dedicated to creating transformative molecular and cell-based therapies for a wide range of human diseases.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008568-25
Application #
9728994
Study Section
NIGMS Initial Review Group (TWD)
Program Officer
Nie, Zhongzhen
Project Start
1995-07-01
Project End
2020-06-30
Budget Start
2019-07-01
Budget End
2020-06-30
Support Year
25
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Pathology
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94118
Chitre, Avantika S; Kattah, Michael G; Rosli, Yenny Y et al. (2018) A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function. PLoS Pathog 14:e1006806
Rana, Manish K; Aloisio, Francesca M; Choi, Changhoon et al. (2018) Formin-dependent TGF-? signaling for epithelial to mesenchymal transition. Mol Biol Cell 29:1465-1475
Mancini, Andrew; Xavier-Magalhães, Ana; Woods, Wendy S et al. (2018) Disruption of the ?1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner. Cancer Cell 34:513-528.e8
Emmerson, Elaine; May, Alison J; Berthoin, Lionel et al. (2018) Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement. EMBO Mol Med 10:
Donnella, Hayley J; Webber, James T; Levin, Rebecca S et al. (2018) Kinome rewiring reveals AURKA limits PI3K-pathway inhibitor efficacy in breast cancer. Nat Chem Biol 14:768-777
Ye, Wenlei; Han, Tina W; Nassar, Layla M et al. (2018) Phosphatidylinositol-(4, 5)-bisphosphate regulates calcium gating of small-conductance cation channel TMEM16F. Proc Natl Acad Sci U S A 115:E1667-E1674
Chang, Roger; Eriksen, Jacob; Edwards, Robert H (2018) The dual role of chloride in synaptic vesicle glutamate transport. Elife 7:
Saiki, Julie P; Cao, Hongbin; Van Wassenhove, Lauren D et al. (2018) Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes. Proc Natl Acad Sci U S A 115:6279-6284
Durack, Juliana; Kimes, Nikole E; Lin, Din L et al. (2018) Delayed gut microbiota development in high-risk for asthma infants is temporarily modifiable by Lactobacillus supplementation. Nat Commun 9:707
Smith, Lucas K; White 3rd, Charles W; Villeda, Saul A (2018) The systemic environment: at the interface of aging and adult neurogenesis. Cell Tissue Res 371:105-113

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