The Predoctoral Training Program in Genetics at the University of Iowa has a 40-year history during which more than 80 students have graduated with a Ph.D. The program currently serves 67 faculty and 44 students in four colleges and 18 academic departments across our campus. Since the time of the last competitive submission of this application, our interdisciplinary faculty has grown by 12 with an average of 8 new students entering the program each year. We have an enviable record of student retention, on-time graduation rates, publications and awards, as well as career advancement to postdoctoral fellowships and faculty positions at research-intensive universities. Of particular note is the central role that our program has played in building graduate programs in comparative genomics and bioinformatics on campus. We have seen growth and solidification of the nascent Computational Genetics subtrack option in the Genetics Ph.D., with now seven students that have already graduated from the track, four of which are already in faculty positions. We have made recent progress in diversifying our student population, and incorporated several strategies to build on a nucleus of minority students, as well as to enhance the retention of these and indeed all students in the program. In this renewal application we request a continuation of the six fellowship slots we currently have available to serve our cadre of high quality and productive students. This application will outline our successes over the last 40 years of program existence, our current structure, and plans for future improvements in diversity, graduation times and mentoring. We have a cohesive group of students working with a broad and diverse collection of faculty who represent the genetics community in all its facets. Finally we have stable program leadership at both the faculty and administrative level and very strong support within the graduate college that helps to ensure not only the continued success of the program but its further strengthening and diversification at a time when scientific careers are proving increasingly challenging.

Public Health Relevance

The purpose of the Predoctoral Training Program in Genetics is to optimally prepare students, in the process of achieving the Ph.D., for meeting and leading the ongoing and upcoming trends in Genetics research. Our mission for society is to generate scientists that can be at the forefront of Genetics research, who can in turn contribute to trainin and collaborating with physicians and other allied health professionals, and who can educate all members of society that will increasingly need to understand genetic aspects of their own family's health care and individualized genomes. Because this need is among people from all walks of life, we emphasize diversity in our Ph.D. students. With the pervasive implications of the individualized genome, including both the promises and the dangers of exploiting the information therein, the need to train competent Ph.D. students is paramount.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008629-17
Application #
8492103
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Carter, Anthony D
Project Start
1997-07-01
Project End
2017-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
17
Fiscal Year
2013
Total Cost
$189,927
Indirect Cost
$12,735
Name
University of Iowa
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Spring, Ashlyn M; Brusich, Douglas J; Frank, C Andrew (2016) C-terminal Src Kinase Gates Homeostatic Synaptic Plasticity and Regulates Fasciclin II Expression at the Drosophila Neuromuscular Junction. PLoS Genet 12:e1005886
Chen, Linxiao; Valentine, Jenny L; Huang, Chung-Jr et al. (2016) Outer membrane vesicles displaying engineered glycotopes elicit protective antibodies. Proc Natl Acad Sci U S A 113:E3609-18
Weirather, Jason L; Duggal, Priya; Nascimento, Eliana L et al. (2016) Fine mapping under linkage peaks for symptomatic or asymptomatic outcomes of Leishmania infantum infection in Brazil. Infect Genet Evol 43:1-5
Leslie, Elizabeth J; O'Sullivan, James; Cunningham, Michael L et al. (2015) Expanding the genetic and phenotypic spectrum of popliteal pterygium disorders. Am J Med Genet A 167A:545-52
Leslie, Elizabeth J; Taub, Margaret A; Liu, Huan et al. (2015) Identification of functional variants for cleft lip with or without cleft palate in or near PAX7, FGFR2, and NOG by targeted sequencing of GWAS loci. Am J Hum Genet 96:397-411
Olsen, Daniel S; Goar, Wesley A; Nichols, Brandt A et al. (2015) Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model. Biomed Res Int 2015:975789
Peyrard-Janvid, Myriam; Leslie, Elizabeth J; Kousa, Youssef A et al. (2014) Dominant mutations in GRHL3 cause Van der Woude Syndrome and disrupt oral periderm development. Am J Hum Genet 94:23-32
Jones, Bradley D; Faron, Matthew; Rasmussen, Jed A et al. (2014) Uncovering the components of the Francisella tularensis virulence stealth strategy. Front Cell Infect Microbiol 4:32
Herrig, Danielle K; Modrick, Alec J; Brud, Evgeny et al. (2014) Introgression in the Drosophila subobscura--D. Madeirensis sister species: evidence of gene flow in nuclear genes despite mitochondrial differentiation. Evolution 68:705-19
Sharma, Tasneem P; McDowell, Colleen M; Liu, Yang et al. (2014) Optic nerve crush induces spatial and temporal gene expression patterns in retina and optic nerve of BALB/cJ mice. Mol Neurodegener 9:14

Showing the most recent 10 out of 45 publications