This is a competitive renewal of a training program in Developmental Hematology in the Department of Pediatrics at Washington University School of Medicine. The program will provide pediatric physicians (MD's or MD, PhD's) with postdoctoral research experience with the long-term goal of producing independent investigators capable of making important contributions to biomedical research. The program will support one second-year (PGY-4) and one third-year fellow (PGY-5) each year. The trainees will be recruited from the Hematology-Oncology fellowship program in the Department of Pediatrics at Washington University School of Medicine. The fellowship program is comprised of three to four years of training, only two of which will be supported by the T32. The Hematology-Oncology fellowship includes many qualified applicants with backgrounds in hematology research. Trainees will participate in a formal seminar series that includes a discussion of current research in developmental hematology, along with didactic sessions in statistics, design of research, and the ethical conduct of research. Trainees may perform their postdoctoral research in a wide range of laboratories at Washington University, provided the research is relevant to the field of developmental hematology. The Program offers trainees two Pathways. In Pathway A, the emphasis is on basic science genetics/genomics experiences, a core curriculum, and a basic-science curriculum. In Pathway B, the emphasis is on clinical/translational genomic science with patient-oriented laboratory-based experiences, a core curriculum and a clinical investigation, translational medicine or genetics/genomics curriculum. Alan L. Schwartz, MD, PhD, will serve as Program Director. The continued support of this program will help to close the gap between basic developmental biologists and pediatrician clinicians.

Public Health Relevance

This training program is designed to bridge the gap between clinical and basic scientists. The focus of this program is the training of physician scientists in basic and applied research relevant to the causes of hematologic diseases in children. Qualified trainees, both MD's and MD/PhD's, will be selected for their potential to assume academic positions in pediatric departments at major medical schools. The training program compliments existing programs in the Department of Pediatrics designed to enhance training in developmental biology and animal models of disease.

Agency
National Institute of Health (NIH)
Type
Institutional National Research Service Award (T32)
Project #
2T32HD007499-16A1
Application #
8853052
Study Section
Special Emphasis Panel (ZHD1)
Program Officer
Grave, Gilman D
Project Start
Project End
Budget Start
Budget End
Support Year
16
Fiscal Year
2015
Total Cost
Indirect Cost
Name
Washington University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
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