The purpose of the Developmental and Stem Cell Biology Training Program (DSCB) is to prepare PhD candidates for participation as active scientists in disciplines having an emphasis on developmental biology, stem cell biology and developmental genetics. To accomplish this goal, the training program provides education in core principles of development, genetics, cell biology and molecular biology. Of special importance is the preparation of critical and creative minds. In addition to didactic training, the Program provides and encourages participation in a number of seminars, journal clubs and colloquia that foster discussion, perspective and critical review of the literature. Extensive laboratory training provides each student with a special expertise in his or her chosen specialty. Finally, an interactive environment and collaborations with clinical departments fosters the movement of the discovery process to treatments that will improve the human condition.

National Institute of Health (NIH)
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (ZHD1-DRG-D (55))
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Javois, Lorette Claire
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Duke University
Schools of Arts and Sciences
United States
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Martik, Megan L; McClay, David R (2017) New insights from a high-resolution look at gastrulation in the sea urchin, Lytechinus variegatus. Mech Dev 148:3-10
Lin, Yi-Tzu; Barske, Lindsey; DeFalco, Tony et al. (2017) Numb regulates somatic cell lineage commitment during early gonadogenesis in mice. Development 144:1607-1618
Gomez-Pastor, Rocio; Burchfiel, Eileen T; Neef, Daniel W et al. (2017) Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease. Nat Commun 8:14405
Cordero, Francisco J; Huang, Zhiqing; Grenier, Carole et al. (2017) Histone H3.3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPG. Mol Cancer Res 15:1243-1254
Sayour, Elias J; De Leon, Gabriel; Pham, Christina et al. (2017) Systemic activation of antigen-presenting cells via RNA-loaded nanoparticles. Oncoimmunology 6:e1256527
Linden, Lara M; Gordon, Kacy L; Pani, Ariel M et al. (2017) Identification of regulators of germ stem cell enwrapment by its niche in C. elegans. Dev Biol 429:271-284
Martik, Megan L; Lyons, Deirdre C; McClay, David R (2016) Developmental gene regulatory networks in sea urchins and what we can learn from them. F1000Res 5:
Pham, Christina D; Flores, Catherine; Yang, Changlin et al. (2016) Differential Immune Microenvironments and Response to Immune Checkpoint Blockade among Molecular Subtypes of Murine Medulloblastoma. Clin Cancer Res 22:582-95
Chen, Chen-Hui; Puliafito, Alberto; Cox, Ben D et al. (2016) Multicolor Cell Barcoding Technology for Long-Term Surveillance of Epithelial Regeneration in Zebrafish. Dev Cell 36:668-80
Pilaz, Louis-Jan; Lennox, Ashley L; Rouanet, Jeremy P et al. (2016) Dynamic mRNA Transport and Local Translation in Radial Glial Progenitors of the Developing Brain. Curr Biol 26:3383-3392

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