Purpose: This program trains individuals with doctoral degrees in either biological or medical sciences for successful academic careers in research and teaching. We use a multidisciplinary team approach to both mentoring and research training, emphasizing the integration of studies at the molecular, cellular, tissue/organ, and physiological (in vivo) levels. Resources: The senior faculty comprises a mix of PhD and MD preceptors that have distinguished academic records and are well funded by grants from NIH and other organizations. Training occurs primarily in the Cardiovascular Pulmonary Research Laboratory, Developmental Lung Biology Laboratory, Center for Genetic Lung Disease, and Women's Health Research Center at UCDHSC. Adjunctive facilities are also available in various basic science and clinical departments at UCDHSC, the VA Medical Center, the National Jewish Center for Immunology and Respiratory Medicine, the University of Colorado at Boulder, and Children's Hospital. These facilities provide trainees with access to a myriad of physiological, cellular, biochemical, molecular, bioinfomatics/biostatistical expertise, techniques, and equipment. Program: The PhD, MD, and DVM trainees are selected from a pool of applicants comprising graduates of basic science departments from around the country and clinical fellows of the UCDHSC's Divisions of Pulmonary Sciences/Critical Care Medicine, Pediatric Critical Care Medicine, and Cardiology. Selection is based on the candidate's academic credentials, prior research experience, and evidence of enthusiasm and aptitude for a career in biomedical research. In addition to training in laboratory analytical techniques, our trainees receive extensive instruction and experience in study rationale and design, statistical analysis of data, and both oral and written communication. The length of training is three years, and the trainees are strongly encouraged to apply for individual fellowships and start-up grants within the second year of their fellowship. The program director, with the advice and consent of the senior program faculty is responsible for the administration and coordination of the program.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007171-35
Application #
8099437
Study Section
Special Emphasis Panel (ZHL1-CSR-J (F1))
Program Officer
Colombini-Hatch, Sandra
Project Start
1976-07-01
Project End
2013-06-30
Budget Start
2011-07-01
Budget End
2013-06-30
Support Year
35
Fiscal Year
2011
Total Cost
$1
Indirect Cost
Name
University of Colorado Denver
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Tomko, Lucas A; Hill, Ryan C; Barrett, Alexander et al. (2018) Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma. Sci Rep 8:12941
Chicco, Adam J; Le, Catherine H; Gnaiger, Erich et al. (2018) Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics. J Biol Chem 293:6659-6671
Keller, A C; Knaub, L A; Scalzo, R L et al. (2018) Sepiapterin Improves Vascular Reactivity and Insulin-Stimulated Glucose in Wistar Rats. Oxid Med Cell Longev 2018:7363485
Graham, Brian B; Kumar, Rahul; Mickael, Claudia et al. (2018) Vascular Adaptation of the Right Ventricle in Experimental Pulmonary Hypertension. Am J Respir Cell Mol Biol 59:479-489
Almodovar, Sharilyn; Swanson, Jessica; Giavedoni, Luis D et al. (2018) Lung Vascular Remodeling, Cardiac Hypertrophy, and Inflammatory Cytokines in SHIVnef-Infected Macaques. Viral Immunol 31:206-222
Reisz, Julie A; Barrett, Alexander S; Nemkov, Travis et al. (2018) When nature's robots go rogue: exploring protein homeostasis dysfunction and the implications for understanding human aging disease pathologies. Expert Rev Proteomics 15:293-309
Ferguson, Scott K; Harral, Julie W; Pak, David I et al. (2018) Impact of cell-free hemoglobin on contracting skeletal muscle microvascular oxygen pressure dynamics. Nitric Oxide 76:29-36
Wahl, Matthew P; Scalzo, Rebecca L; Regensteiner, Judith G et al. (2018) Mechanisms of Aerobic Exercise Impairment in Diabetes: A Narrative Review. Front Endocrinol (Lausanne) 9:181
Zhang, Hui; Wang, Daren; Li, Min et al. (2017) Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis. Circulation 136:2468-2485
Kumar, Rahul; Mickael, Claudia; Kassa, Biruk et al. (2017) TGF-? activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension. Nat Commun 8:15494

Showing the most recent 10 out of 128 publications