This application is for renewal of an existing institutional training grant that provides an opportunity for post- doctoral trainees to acquire the basic knowledge, understanding, and skills necessary to conduct independent investigation relevant to the etiology and treatment of lung diseases. The program is centered in the Division of Pulmonary and Critical Care Medicine but includes participating faculty in the Departments of Biochemistry, Cell Biology, Immunology, Pathology, Genetics, Pediatrics, and Pharmacology. The training program currently supports 5 postdoctoral (M.D. and/or Ph.D.) trainees annually and is requesting to increase the number of postdoctoral positions to 8. The request of 8 postdoctoral positions is based on the: 1) the outstanding candidates that are eligible for support by our research training program;2) the inability to provide support for all deserving trainees in pulmonary research;3) the successful track record of the trainees;4) the creation of a new research track in molecular and human genetics of lung disease;and 5) the success of the minority recruitment program. The director, co-director, and research track leaders of the program assume an oversight responsibility, and mentorship committees are established to follow the progress and develop the career of each of the trainees. The three major research areas available for the trainees include: Track I - Pulmonary Molecular Biology and Signaling;Track II - Pulmonary Cell Biology and Immunology;and Track III - Molecular and Human Genetics of Lung Disease. Each trainee works under the direct supervision of a specific research preceptor but is also expected to participate in a structured training program that includes didactic teaching sessions, weekly work-in-progress research seminars, invited lecturers, and Duke University course work designed to augment the academic background of trainees. The program is intended to optimally prepare trainees for academic research careers wherein they will be able to acquire and maintain independent funding in a highly competitive research environment.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007538-30
Application #
8502278
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Colombini-Hatch, Sandra
Project Start
1982-07-01
Project End
2014-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
30
Fiscal Year
2013
Total Cost
$349,721
Indirect Cost
$38,389
Name
Duke University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Genao, Liza; Durheim, Michael T; Mi, Xiaojuan et al. (2015) Early and Long-term Outcomes of Older Adults after Acute Care Encounters for Chronic Obstructive Pulmonary Disease Exacerbation. Ann Am Thorac Soc 12:1805-12
Smith, P J; Rivelli, S K; Waters, A M et al. (2015) Delirium affects length of hospital stay after lung transplantation. J Crit Care 30:126-9
Choi, Philip J; Curlin, Farr A; Cox, Christopher E (2015) ""The Patient Is Dying, Please Call the Chaplain"": The Activities of Chaplains in One Medical Center's Intensive Care Units. J Pain Symptom Manage 50:501-6
Durheim, Michael T; Smith, Patrick J; Babyak, Michael A et al. (2015) Six-minute-walk distance and accelerometry predict outcomes in chronic obstructive pulmonary disease independent of Global Initiative for Chronic Obstructive Lung Disease 2011 Group. Ann Am Thorac Soc 12:349-56
Durheim, Michael T; Collard, Harold R; Roberts, Rhonda S et al. (2015) Association of hospital admission and forced vital capacity endpoints with survival in patients with idiopathic pulmonary fibrosis: analysis of a pooled cohort from three clinical trials. Lancet Respir Med 3:388-96
Vickery, Brian P; Scurlock, Amy M; Kulis, Michael et al. (2014) Sustained unresponsiveness to peanut in subjects who have completed peanut oral immunotherapy. J Allergy Clin Immunol 133:468-75
Smith, Patrick J; Rivelli, Sara; Waters, Alexa et al. (2014) Neurocognitive changes after lung transplantation. Ann Am Thorac Soc 11:1520-7
Blumenthal, James A; Emery, Charles F; Smith, Patrick J et al. (2014) The effects of a telehealth coping skills intervention on outcomes in chronic obstructive pulmonary disease: primary results from the INSPIRE-II study. Psychosom Med 76:581-92
Barkauskas, Christina E; Cronce, Michael J; Rackley, Craig R et al. (2013) Type 2 alveolar cells are stem cells in adult lung. J Clin Invest 123:3025-36
Yu, Yen-Rei A; Mao, Lan; Piantadosi, Claude A et al. (2013) CCR2 deficiency, dysregulation of Notch signaling, and spontaneous pulmonary arterial hypertension. Am J Respir Cell Mol Biol 48:647-54

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