This application requests continued support for the highly successful postdoctoral training program in cardiovascular research in the Division of Cardiology at Emory University School of Medicine. The proposed program will extend our laboratory, translational and clinical research curriculum that has developed an impressive record of training outstanding postdoctoral fellows. The Emory University Cardiology Research Division has become recognized as a leader in research on the role of oxidative stress in vascular disease. The trainees of this program have been very successful in obtaining independent positions in academics. In the last 10 years of this training grant, eleven graduates (20%) of our program are faculty members in American medical schools. We have had several fellows who have been winners or finalists for national young investigator awards. Two years of funding are requested for 8 post-doctoral fellows. The 25 mentors included in this application provide a broad-based, multidisciplinary environment ideally suited to provide an outstanding educational experience for trainees. Participating faculty are drawn from the Divisions/Departments of Cardiology, Radiology, Biochemistry, Biomedical Engineering, and the Winship Cancer Center at Emory University. All have established funding and publication records as well as documented success in training productive members of the scientific community. The training program is structured around a mentor-based environment supplemented with an extensive array of didactic educational opportunities. In summary, the proposed cardiovascular research training program will provide a unique opportunity for multidisciplinary training in basic and clinical vascular biology. Successful trainees will be well equipped to initiate a research career in academic cardiology.
We propose to conduct a training program in the Division of Cardiology at Emory University School of Medicine over the next five years that will extend our laboratory, transitional and clinical research curriculum that has developed outstanding postdoctoral fellows over the previous five years. The 25 mentors that have agreed to support the training grant come from many different Departments and Divisions at the University allowing the training fellows a more diverse learning experience. Emerging the fellows into this multidisciplinary environment will allow for better equipped research careers in academic cardiology.
|Lee, Grace Sanghee; Salazar, Hector F; Joseph, Giji et al. (2018) Osteopontin isoforms differentially promote arteriogenesis in response to ischemia via macrophage accumulation and survival. Lab Invest :|
|Al-Badri, Ahmed; Hashmath, Zeba; Oldland, Garrett H et al. (2018) Poor Glycemic Control Is Associated With Increased Extracellular Volume Fraction in Diabetes. Diabetes Care 41:2019-2025|
|Kumar, Arnav; Hung, Olivia Y; Piccinelli, Marina et al. (2018) Low Coronary Wall Shear Stress Is Associated With Severe Endothelial Dysfunction in Patients With Nonobstructive Coronary Artery Disease. JACC Cardiovasc Interv 11:2072-2080|
|Forrester, Steven J; Kikuchi, Daniel S; Hernandes, Marina S et al. (2018) Reactive Oxygen Species in Metabolic and Inflammatory Signaling. Circ Res 122:877-902|
|Paredes, Felipe; Sheldon, Kely; Lassègue, Bernard et al. (2018) Poldip2 is an oxygen-sensitive protein that controls PDH and ?KGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer. Proc Natl Acad Sci U S A 115:1789-1794|
|Xie, Joe X; Eshtehardi, Parham; Varghese, Tina et al. (2017) Prognostic Significance of Nonobstructive Left Main Coronary Artery Disease in Women Versus Men: Long-Term Outcomes From the CONFIRM (Coronary CT Angiography Evaluation For Clinical Outcomes: An International Multicenter) Registry. Circ Cardiovasc Imaging 10:|
|Eshtehardi, Parham; Brown, Adam J; Bhargava, Ankit et al. (2017) High wall shear stress and high-risk plaque: an emerging concept. Int J Cardiovasc Imaging 33:1089-1099|
|Agarwal, Udit; George, Alex; Bhutani, Srishti et al. (2017) Experimental, Systems, and Computational Approaches to Understanding the MicroRNA-Mediated Reparative Potential of Cardiac Progenitor Cell-Derived Exosomes From Pediatric Patients. Circ Res 120:701-712|
|Virag, Lana; Wilson, John S; Humphrey, Jay D et al. (2017) Potential biomechanical roles of risk factors in the evolution of thrombus-laden abdominal aortic aneurysms. Int J Numer Method Biomed Eng 33:|
|Hansen, Laura M; Gupta, Divya; Joseph, Giji et al. (2017) The receptor for advanced glycation end products impairs collateral formation in both diabetic and non-diabetic mice. Lab Invest 97:34-42|
Showing the most recent 10 out of 45 publications