This is a proposal for the competing continuation of the University of Pittsburgh Training Program in Cardiovascular Disease Epidemiology. Advances in noninvasive methods of measuring atherosclerosis and arteriosclerosis have changed the field of CV epidemiology by providing more precise and useful phenotypes for CVD expression. Technology is constantly changing, requiring new protocols to match the capabilities of new equipment. Under the leadership of Dr. Kim Sutton-Tyrrell, this program is designed to provide concentrated training in the quality collection of subclinical atherosclerosis measures and how they can be used to understand the process of atherosclerosis. The training program is organized around four major research strengths: vascular aging, women's health, high risk and international populations and genetics. The unifying theme is the application of subclinical atherosclerosis measures to each research area. Core strengths in nutrition, exercise, biostatistics, multi- center collaborations and psychosocial measures are also integrated into the program. This interconnected set of resources provides a rich substrate upon which the trainees develop. Trainees have a primary mentor and will also work closely with other faculty members as well as a peer mentor who is a more experienced trainee. The training program consists of course work, research field work and professional development, all individually tailored to each trainee. Research field work includes recruitment, data collection, entry and management, study operations and data analysis, providing trainees with experience in the full range of research tasks. Professional development activities include focused work with subclinical measures, completion of an independent research project, a remote training experience, grant writing experience, manuscript preparation, participation in national conferences, skill development workshops and training in the responsible conduct of research. Trainees will also have the opportunity to develop laboratory-based and analytical skills in genetic epidemiology. The program is designed to produce investigators skilled in a multidisciplinary approach to cardiovascular research, who are comfortable with using subclinical measures in cross-discipline collaborations and who have the skills to develop new measurement protocols.
This training program will produce investigators skilled in a multidisciplinary approach to cardiovascular research, who are comfortable with using subclinical measures of cardiovascular disease and who have the skills to develop new measurement protocols. This will move the field of cardiovascular epidemiology forward by encouraging research using more precise phenotypes for cardiovascular disease.
|Shaaban, C E; Aizenstein, H J; Jorgensen, D R et al. (2017) In Vivo Imaging of Venous Side Cerebral Small-Vessel Disease in Older Adults: An MRI Method at 7T. AJNR Am J Neuroradiol 38:1923-1928|
|Cortés, Yamnia I; Reame, Nancy; Zeana, Cosmina et al. (2017) Cardiovascular Risk in HIV-Infected and Uninfected Postmenopausal Minority Women: Use of the Framingham Risk Score. J Womens Health (Larchmt) 26:241-248|
|Jonassaint, Charles R; Birenboim, Amit; Jorgensen, Dana Rae et al. (2017) The association of smartphone-based activity space measures with cognitive functioning and pain sickle cell disease. Br J Haematol :|
|Cortés, Yamnia I; Arcia, Adriana; Kearney, Joan et al. (2017) Urban-Dwelling Community Members' Views on Biomedical Research Engagement. Qual Health Res 27:130-137|
|Meyer, Michelle L; Tepper, Ping G; Barinas-Mitchell, Emma et al. (2016) Varying patterns of brachial artery flow-mediated dilatation in women with polycystic ovary syndrome and controls: An application of the group-based trajectory modeling. J Clin Ultrasound 44:46-54|
|Kuipers, A L; Miljkovic, I; Evans, R et al. (2016) Optimal serum cholesterol concentrations are associated with accelerated bone loss in African ancestry men. Osteoporos Int 27:1577-84|
|Kuipers, Allison L; Kammerer, Candace M; Pratt, J Howard et al. (2016) Association of Circulating Renin and Aldosterone With Osteocalcin and Bone Mineral Density in African Ancestry Families. Hypertension 67:977-82|
|Jorgensen, Dana R; Rosano, Caterina; Novelli, Enrico M (2016) Can Neuroimaging Markers of Vascular Pathology Explain Cognitive Performance in Adults With Sickle Cell Anemia? A review of the Literature. Hemoglobin 40:381-387|
|Fisher, William I; Thurston, Rebecca C (2016) Measuring hot flash phenomenonology using ambulatory prospective digital diaries. Menopause 23:1222-1227|
|Ahuja, Vasudha; Masaki, Kamal; Barinas-Mitchell, Emma J M et al. (2016) Significantly Greater Progression of Intima-Media Thickness of the Carotid Artery in Japanese American Men Than in White Men: The ERA JUMP Study. Can J Cardiol 32:1246.e7-1246.e12|
Showing the most recent 10 out of 34 publications