The Clinician-Scientist Training Program in Cardiovascular Medicine at The University of North Carolina at Chapel Hill (UNC-CH) is designed to provide two years of concentrated research training for future cardiologists who wish to pursue careers as academic Clinician-Scientists. It is primarily focused on providing additional training in basic science and/or translational research to physicians whose clinical specialty will be cardiology while also accommodating cardiac surgeons or other physicians interested in pursuing a career in an academic field involving cardiovascular disease. The Training Program brings together faculty from basic science and clinical disciplines and includes several mentors who were recipients of NRSA funding during their training. During the current funding cycle, the training program has supported a total of nine trainees including 3 MD, PhD, 2 MD, MSc, 3 MD and 1 PhD. There have been four women and five men. Eight of the trainees are physicians with five pursuing clinical training in Cardiology, one in General Surgery, one in Rheumatology/Allergy and Immunology and one in Nuclear Medicine. Of the five individuals who are training to be cardiologists, two of these physicians have a PhD and four spent at least one year of dedicated time pursuing basic science research prior to entering the Training Program. The trainees have been successful in their work and have published and made presentations at national meetings at an impressive rate. One of the physicians who finished clinical training in 2010 embarked upon academic career;because of the relative newness of the Training Program, none of the other trainees have completed all of their clinical and research training. In this application, we are requesting that the Clinician-Scientist Training Program in Cardiovascular Medicine be funded for a second five year period.

Public Health Relevance

The Clinician-Scientist Training Program in Cardiovascular Medicine at The University of North Carolina at Chapel Hill (UNC-CH) is designed to provide research experience for physicians training to be cardiologists to prepare them for a career as academic Clinician-Scientists. It provides two years of concentrated training in basic science and/or translational research to physicians who are training to become cardiologists while also accommodating cardiac surgeons or other physicians interested in pursuing a career in an academic field involving cardiovascular disease. The goal of the program is to train Cardiologists to perform research that will lead to new treatments as they care for the medical needs of their patients.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL083828-09
Application #
8688314
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Scott, Jane
Project Start
2006-06-01
Project End
2016-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
9
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Dai, Xuming; Wiernek, Szymon; Evans, James P et al. (2016) Genetics of coronary artery disease and myocardial infarction. World J Cardiol 8:1-23
Burk, Laurel M; Wang, Ko-Han; Wait, John Matthew et al. (2015) Delayed contrast enhancement imaging of a murine model for ischemia reperfusion with carbon nanotube micro-CT. PLoS One 10:e0115607
Chang, Emily H; Gasim, Adil H; Kerber, Michael L et al. (2015) Palladin is upregulated in kidney disease and contributes to epithelial cell migration after injury. Sci Rep 5:7695
Zhou, Ruihai; Stouffer, George A (2014) Is time of renal hypoperfusion an important variable in determining response to renal artery revascularization? JACC Cardiovasc Interv 7:110
Willis, Monte S; Wadosky, Kristine M; Rodriguez, Jessica E et al. (2014) Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1-mediated gene expression in vivo. Cell Biochem Funct 32:39-50
Dyer, Laura; Wu, Yaxu; Moser, Martin et al. (2014) BMPER-induced BMP signaling promotes coronary artery remodeling. Dev Biol 386:385-94
Rubel, Carrie E; Schisler, Jonathan C; Hamlett, Eric D et al. (2013) Diggin' on u(biquitin): a novel method for the identification of physiological E3 ubiquitin ligase substrates. Cell Biochem Biophys 67:127-38
Rein-Smith, Chantelle M; Anderson, Nathan W; Farrell, David H (2013) Differential regulation of fibrinogen γ chain splice isoforms by interleukin-6. Thromb Res 131:89-93
Pi, Xinchun; Lockyer, Pamela; Dyer, Laura A et al. (2012) Bmper inhibits endothelial expression of inflammatory adhesion molecules and protects against atherosclerosis. Arterioscler Thromb Vasc Biol 32:2214-22
Zhou, Rui-Hai; Vendrov, Aleksandr E; Tchivilev, Igor et al. (2012) Mitochondrial oxidative stress in aortic stiffening with age: the role of smooth muscle cell function. Arterioscler Thromb Vasc Biol 32:745-55

Showing the most recent 10 out of 24 publications