This T32 Vascular Surgery Education and Research Training (VascTrain) Program is designed to train vascular surgery residents in the fundamentals of basic and clinical cardiovascular research. This will be accomplished using a training committee comprised of a principal trainer and a team of associate trainers in a closely supervised training program. The training scheme is based on interactions between the training committee and the trainee in the form of weekly training research sessions. The VascTrain Program is integrated into a Vascular Surgery residency program where all residents participate in a 2 year curriculum designed to provide research training. Funding for 3 positions is sought to support trainees who will enter the program after 3 years of vascular surgery or surgery residency. A few PhD post-doctoral fellows will be accepted into this program. The research areas of focus are based on cardiovascular diseases, its consequences and its treatments. General areas of investigation include the pathogenesis and treatment of intimal hyperplasia, tissue engineered autologous conduits, tissue ischemia induced angiogenesis and wound healing, computational analysis of aortic aneurysm progress and rupture, cardiovascular imaging, epidemiology of cardiovascular disease, and pharmacotherapeutics. The program introduces a multidisciplinary approach to vascular biology research and a dedicated approach to clinical/translational research.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL098036-05
Application #
8699816
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Scott, Jane
Project Start
2010-07-01
Project End
2015-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
5
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Surgery
Type
Schools of Medicine
DUNS #
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Liang, Nathan L; Alarcon, Louis H; Jeyabalan, Geetha et al. (2016) Contemporary outcomes of civilian lower extremity arterial trauma. J Vasc Surg 64:731-6
Tillman, Bryan W; Chun, Youngjae; Cho, Sung Kwon et al. (2016) Dual chamber stent prevents organ malperfusion in a model of donation after cardiac death. Surgery 160:892-901
Genovese, Elizabeth A; Chaer, Rabih A; Taha, Ashraf G et al. (2016) Risk Factors for Long-Term Mortality and Amputation after Open and Endovascular Treatment of Acute Limb Ischemia. Ann Vasc Surg 30:82-92
McEnaney, Ryan M; Shukla, Ankur; Madigan, Michael C et al. (2016) P2Y2 nucleotide receptor mediates arteriogenesis in a murine model of hind limb ischemia. J Vasc Surg 63:216-25
Haskett, Darren G; Maestas, David; Howerton, Stephen J et al. (2016) 2-Photon Characterization of Optical Proteolytic Beacons for Imaging Changes in Matrix-Metalloprotease Activity in a Mouse Model of Aneurysm. Microsc Microanal 22:349-60
Liang, Nathan L; Avgerinos, Efthymios D; Hager, Eric S et al. (2016) Endovascular Repair of an Iliac Ureteroarterial Fistula with Late Stent Thrombosis and Migration into the Bladder. Ann Vasc Surg 35:204.e5-7
Genovese, Elizabeth A; Avgerinos, Efthymios D; Baril, Donald T et al. (2016) Bio-absorbable antibiotic impregnated beads for the treatment of prosthetic vascular graft infections. Vascular 24:590-597
Liang, Nathan L; Guedes, Brian D; Duvvuri, Umamaheswar et al. (2016) Outcomes of interventions for carotid blowout syndrome in patients with head and neck cancer. J Vasc Surg 63:1525-30
Xu, Jia; Benabou, Kelly; Cui, Xiangdong et al. (2015) TLR4 Deters Perfusion Recovery and Upregulates Toll-like Receptor 2 (TLR2) in Ischemic Skeletal Muscle and Endothelial Cells. Mol Med 21:605-15
Madigan, Michael; Entabi, Fateh; Zuckerbraun, Brian et al. (2015) Delayed inhaled carbon monoxide mediates the regression of established neointimal lesions. J Vasc Surg 61:1026-33

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