There is a need for training of more academic hematologists/oncologists. A national survey of training directors showed that less than one third of graduates of adult hematology/oncology programs went into academic research. The proposed Hematology Post-Doctoral Training program will address many issues raised by graduates. We will offer inter and multi-disciplinary training in hematology, a mix of mentors who are both senior and junior and of both genders, programs that intermingle clinical and basic research with a concerted focus on the development of outstanding hematologic investigators, abundant state of the art technologies and a dedication to teaching and developing outstanding academic hematologists. We plan to train physicians and scientists for careers in academic medicine and hematology related research. Our trainees will be exposed to the art of clinical medicine and the rigorous disciplines of basic laboratory, population science or clinical translation research. Trainees will be expected to interact, formulate hypotheses, critically evaluate both clinical and basic literature and develop new diagnostic and therapeutic approaches. This training program will provide the 2 years of support for up to 4 trainees.

Public Health Relevance

Intensive research training of doctors and scientists in blood diseases is critical for forming a base to develop treatments and cures for a wide variety of blood diseases including leukemia, lymphoma, myeloma, hemophilia, aplastic anemia and a wide variety of anemias and blood clotting disorders. This training program will prepare hematologists and scientists to develop new hypotheses on disease origins and scientifically developed treatment to improve the health and safety of patients with blood diseases.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Chang, Henry
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Rhode Island Hospital
United States
Zip Code
Wen, S; Dooner, M; Cheng, Y et al. (2016) Mesenchymal stromal cell-derived extracellular vesicles rescue radiation damage to murine marrow hematopoietic cells. Leukemia 30:2221-2231
Aliotta, Jason M; Pereira, Mandy; Sears, Edmund H et al. (2015) Lung-derived exosome uptake into and epigenetic modulation of marrow progenitor/stem and differentiated cells. J Extracell Vesicles 4:26166
Prsic, Elizabeth Horn (2015) The other epidemic. R I Med J (2013) 98:14
Quesenberry, Peter J; Aliotta, Jason; Camussi, Giovanni et al. (2015) Potential functional applications of extracellular vesicles: a report by the NIH Common Fund Extracellular RNA Communication Consortium. J Extracell Vesicles 4:27575
Nisimova, Liana; Wen, Sicheng; Cross-Knorr, Sam et al. (2014) Role of Raf kinase inhibitor protein in Helicobacter pylori-mediated signaling in gastric cancer. Crit Rev Oncog 19:469-81