We propose to continue a Jointly Sponsored Predoctoral Training Program in Neurosciences that is the major source of support for early year students in the Ph.D. Program in Neurosciences at Harvard University. The goals of this interdepartmental Ph.D. program, established in 1981, are (1) to organize within a single training faculty the neuroscientists at Harvard Medical School, its affiliated hospitals, and Harvard College;and (2) to train research scientists and teachers who are interested in mental health, diseases of the nervous system, and fundamental mechanisms of the brain. The training program is designed to provide trainees with a broad and thorough background in neuroscience and to mentor them in performing original and rigorous research in important areas of neuroscience. In the first 18 months, trainees complete a sequence of core courses ranging from cell and molecular neurobiology to systems neuroscience, as well as collateral courses selected from cell and molecular biology, immunology, statistics, and other subjects appropriate to individual interests. Students rotate through three different laboratories. Following the coursework, laboratory rotations, and a preliminary examination, students begin full time dissertation research. They are also involved in other ongoing training activities including journa clubs, seminars, and data presentation. There are currently 100 graduate students enrolled in the Program in Neuroscience. The total faculty includes 118 members;the 68 faculty who are currently most actively involved in graduate education are training mentors on this proposal. Considerable effort has gone into making this program a highly interactive group with extensive formal and informal contacts between students and faculty. Graduates of this program have a high rate of staying in careers in biomedical research and make substantial contributions to a growing understanding of neuroscience.
The goals of this interdepartmental Ph.D. program are (1) to organize within a single training faculty the neuroscientists at Harvard Medical School, its affiliated hospitals, and Harvard College;and (2) to train research scientists and teachers who are interested in mental health, diseases of the nervous system, and fundamental mechanisms of the brain.
|Eshel, Neir; Tian, Ju; Bukwich, Michael et al. (2016) Dopamine neurons share common response function for reward prediction error. Nat Neurosci 19:479-86|
|GÃ³mez-Laberge, Camille; Smolyanskaya, Alexandra; Nassi, Jonathan J et al. (2016) Bottom-Up and Top-Down Input Augment the Variability of Cortical Neurons. Neuron 91:540-7|
|Yung, Andrea R; Nishitani, Allison M; Goodrich, Lisa V (2015) Phenotypic analysis of mice completely lacking netrin 1. Development 142:3686-91|
|Ben-Zvi, Ayal; Lacoste, Baptiste; Kur, Esther et al. (2014) Mfsd2a is critical for the formation and function of the blood-brain barrier. Nature 509:507-11|
|Hayworth, Kenneth J; Morgan, Josh L; Schalek, Richard et al. (2014) Imaging ATUM ultrathin section libraries with WaferMapper: a multi-scale approach to EM reconstruction of neural circuits. Front Neural Circuits 8:68|
|Luo, Linjiao; Cook, Nathan; Venkatachalam, Vivek et al. (2014) Bidirectional thermotaxis in Caenorhabditis elegans is mediated by distinct sensorimotor strategies driven by the AFD thermosensory neurons. Proc Natl Acad Sci U S A 111:2776-81|
|Spiegel, Ivo; Mardinly, Alan R; Gabel, Harrison W et al. (2014) Npas4 regulates excitatory-inhibitory balance within neural circuits through cell-type-specific gene programs. Cell 157:1216-29|
|Donahue, Rachel J; Muschamp, John W; Russo, Scott J et al. (2014) Effects of striatal Î”FosB overexpression and ketamine on social defeat stress-induced anhedonia in mice. Biol Psychiatry 76:550-8|
|Reiff, Rachel E; Ali, Bassam R; Baron, Byron et al. (2014) METTL23, a transcriptional partner of GABPA, is essential for human cognition. Hum Mol Genet 23:3456-66|
|Eshel, Neir; Tian, Ju (2014) Dopamine gates sensory representations in cortex. J Neurophysiol 111:2161-3|
Showing the most recent 10 out of 61 publications