The proposal is for the renewal of support for a graduate training program at Vanderbilt University that is structured to support the early phases of neuroscience predoctoral education and training. In support of the overall NIH mission, the overarching objective of the program is to provide an exceptional training environment for the next generation of neuroscientists, and is built on the foundation of a strong training faculty wit exceptional records of scholarship, research support and graduate mentoring. The heart of this mission is expressed in the academic and research goals of the program, which are to provide our students with a strong didactic foundation in the neurosciences through our core curriculum offerings, and to provide them with the opportunity to carry out state-of-the-art neuroscience research in the laboratories of a group of highly successful and committed mentors. In addition, the program has strong emphases on professional development and diversity, with the objective of building the requisite skills needed for success in graduate school and beyond, and of training an inclusive cadre of future independent investigators in neuroscience research. The Neuroscience Graduate Program at Vanderbilt is an interdisciplinary program that encompasses four different colleges and schools and 18 departments. Students can enter the program either directly or via three umbrella "feeder" programs (IGP/MSTP/CPB). Traditional and emerging areas of research strength in the program include: attention, brain evolution, cell signaling, cognitive neuroscience, circadian function, CNS drug development, development and developmental disabilities, molecular genetics, neurodegeneration and neurotoxicity, neuroimaging, plasticity, psychiatric illness, sensory and multisensory systems, synaptic transmission, and vision. The program is currently home to 83 trainees and 64 training faculty. The proposal requests an increase in support from 7 to 10 slots and provides the rationale and justification for this request.

Public Health Relevance

The goals and training philosophy of the Neuroscience Graduate Program at Vanderbilt are congruent with and contribute to the overarching mission of the NIH institutes that support neuroscience research - to transform the understanding and treatment of neurological and mental illnesses through basic and clinical research and the education and training that enable innovative research and discovery. Areas of emphasis within the training program provide opportunity for transformative research and research training at the basic science, clinical and translational levels. The relevance of this training for public health cannot be understated, as it is the education and research training of young scientists that will provide the foundation for future discovery.

Agency
National Institute of Health (NIH)
Type
Institutional National Research Service Award (T32)
Project #
5T32MH064913-12
Application #
8683235
Study Section
Special Emphasis Panel (ZNS1)
Program Officer
Desmond, Nancy L
Project Start
Project End
Budget Start
Budget End
Support Year
12
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Neurosciences
Type
Schools of Medicine
DUNS #
City
Nashville
State
TN
Country
United States
Zip Code
37212
Hardaway, J Andrew; Wang, Jing; Fleming, Paul A et al. (2014) An open-source analytical platform for analysis of C. elegans swimming-induced paralysis. J Neurosci Methods 232:58-62
Bluett, R J; Gamble-George, J C; Hermanson, D J et al. (2014) Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation. Transl Psychiatry 4:e408
Marion, Roan; Li, Keji; Purushothaman, Gopathy et al. (2013) Morphological and neurochemical comparisons between pulvinar and V1 projections to V2. J Comp Neurol 521:813-32
Husson, Steven J; Costa, Wagner Steuer; Wabnig, Sebastian et al. (2012) Optogenetic analysis of a nociceptor neuron and network reveals ion channels acting downstream of primary sensors. Curr Biol 22:743-52
Mitchell, Amanda C; Leak, Rehana K; Garbett, Krassimira et al. (2012) Physical activity-associated gene expression signature in nonhuman primate motor cortex. Obesity (Silver Spring) 20:692-8
Mitchell, Amanda C; Leak, Rehana K; Zigmond, Michael J et al. (2012) Gene transcripts associated with BMI in the motor cortex and caudate nucleus of calorie restricted rhesus monkeys. Genomics 99:144-51
Sakrikar, Dhananjay; Mazei-Robison, Michelle S; Mergy, Marc A et al. (2012) Attention deficit/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation. J Neurosci 32:5385-97
Konradi, Christine; Sillivan, Stephanie E; Clay, Hayley B (2012) Mitochondria, oligodendrocytes and inflammation in bipolar disorder: evidence from transcriptome studies points to intriguing parallels with multiple sclerosis. Neurobiol Dis 45:37-47
Mitchell, Amanda C; Mirnics, Karoly (2012) Gene expression profiling of the brain: pondering facts and fiction. Neurobiol Dis 45:3-7
Zannino, Denise A; Sagerstrom, Charles G; Appel, Bruce (2012) olig2-Expressing hindbrain cells are required for migrating facial motor neurons. Dev Dyn 241:315-26

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