The Neurobiology of Information Storage Training Program (NISTP) is based in the Northwestern University Interdepartmental Neuroscience program (NUIN), emerging from within a multidisciplinary group of highly interactive investigators who have carried out research at different levels, and have successfully engaged in collaborative research on cellular, molecular, structural, network and system determinants of information storage. After the first 2 cycles of NIMH-supported training grant activity it is clear that NISTP is part of the fabric of the neuroscience community at Northwestern. Since its inception in 2003, NISTP has evolved by continually adding elements that enrich the training experience. Training includes a formal didactic component in the form of a special course focusing on the latest research in information storage neurobiology, three special lecture series each with the purpose of bringing the most outstanding scientists to interact with the trainees, a mock study section which provides both professional training and is a springboard for submission of an NRSA proposal (a NISTP requirement), the annual retreat that fosters a wide-range of survival skills with maximum trainee - faculty interaction, two different journal clubs reviewing recent research in the neurobiology of information storage, and a 'Buddy Program'that encourages trainees to see the 'bench-to-bedside'application of their fundamental research. With these value added components, we believe that trainees emerge from the training program both poised to advance research in fundamental biological mechanisms of learning and memory and well-positioned to develop novel translational applications.

Public Health Relevance

The Neurobiology of Information Storage Training Program seeks to train the next generation of scientists that will try to understand, at the most fundamental level, the process of learning and memory. Training will lead not only to understanding how the brain works, but hopefully to treatments and therapies to combat diseases of the brain.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (ZMH1-ERB-S (01))
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Desmond, Nancy L
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Northwestern University at Chicago
Schools of Medicine
United States
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Han, Y; Heuermann, R J; Lyman, K A et al. (2016) HCN-channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects. Mol Psychiatry :
Heuermann, Robert J; Jaramillo, Thomas C; Ying, Shui-Wang et al. (2016) Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy. Neurobiol Dis 85:81-92
Hedrick, Tristan; Danskin, Bethanny; Larsen, Rylan S et al. (2016) Characterization of Channelrhodopsin and Archaerhodopsin in Cholinergic Neurons of Cre-Lox Transgenic Mice. PLoS One 11:e0156596
Nomura, Toshihiro; Oyamada, Yoshihiro; Fernandes, Herman B et al. (2016) Subchronic phencyclidine treatment in adult mice increases GABAergic transmission and LTP threshold in the hippocampus. Neuropharmacology 100:90-7
Bortoletto, Pietro; Lyman, Kyle; Camacho, Andres et al. (2015) Chronic Granulomatous Disease: A Large, Single-center US Experience. Pediatr Infect Dis J 34:1110-4
Morita, Takeshi; McClain, Shannan P; Batia, Lyn M et al. (2015) HTR7 Mediates Serotonergic Acute and Chronic Itch. Neuron 87:124-38
Han, Ye; Lyman, Kyle; Clutter, Matt et al. (2015) Identification of Small-Molecule Inhibitors of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels. J Biomol Screen 20:1124-31
Fernandes, Herman B; Riordan, Sean; Nomura, Toshihiro et al. (2015) Epac2 Mediates cAMP-Dependent Potentiation of Neurotransmission in the Hippocampus. J Neurosci 35:6544-53
Frank, Dominic D; Jouandet, Genevieve C; Kearney, Patrick J et al. (2015) Temperature representation in the Drosophila brain. Nature 519:358-61
Tabatadze, Nino; Huang, Guangzhe; May, Renee M et al. (2015) Sex Differences in Molecular Signaling at Inhibitory Synapses in the Hippocampus. J Neurosci 35:11252-65

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