The Neurobiology of Information Storage Training Program (NISTP) is based in the Northwestern University Interdepartmental Neuroscience program (NUIN), emerging from within a multidisciplinary group of highly interactive investigators who have carried out research at different levels, and have successfully engaged in collaborative research on cellular, molecular, structural, network and system determinants of information storage. After the first 2 cycles of NIMH-supported training grant activity it is clear that NISTP is part of the fabric of the neuroscience community at Northwestern. Since its inception in 2003, NISTP has evolved by continually adding elements that enrich the training experience. Training includes a formal didactic component in the form of a special course focusing on the latest research in information storage neurobiology, three special lecture series each with the purpose of bringing the most outstanding scientists to interact with the trainees, a mock study section which provides both professional training and is a springboard for submission of an NRSA proposal (a NISTP requirement), the annual retreat that fosters a wide-range of survival skills with maximum trainee - faculty interaction, two different journal clubs reviewing recent research in the neurobiology of information storage, and a 'Buddy Program' that encourages trainees to see the 'bench-to-bedside' application of their fundamental research. With these value added components, we believe that trainees emerge from the training program both poised to advance research in fundamental biological mechanisms of learning and memory and well-positioned to develop novel translational applications.

Public Health Relevance

The Neurobiology of Information Storage Training Program seeks to train the next generation of scientists that will try to understand, at the most fundamental level, the process of learning and memory. Training will lead not only to understanding how the brain works, but hopefully to treatments and therapies to combat diseases of the brain.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Institutional National Research Service Award (T32)
Project #
4T32MH067564-14
Application #
9086424
Study Section
Special Emphasis Panel (ZMH1)
Program Officer
Desmond, Nancy L
Project Start
2003-07-01
Project End
2018-06-30
Budget Start
2016-07-01
Budget End
2017-06-30
Support Year
14
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Physiology
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Guo, KuangHua; Yamawaki, Naoki; Svoboda, Karel et al. (2018) Anterolateral Motor Cortex Connects with a Medial Subdivision of Ventromedial Thalamus through Cell Type-Specific Circuits, Forming an Excitatory Thalamo-Cortico-Thalamic Loop via Layer 1 Apical Tuft Dendrites of Layer 5B Pyramidal Tract Type Neurons. J Neurosci 38:8787-8797
Sheffield, Mark E J; Adoff, Michael D; Dombeck, Daniel A (2017) Increased Prevalence of Calcium Transients across the Dendritic Arbor during Place Field Formation. Neuron 96:490-504.e5
Lyman, Kyle A; Han, Ye; Heuermann, Robert J et al. (2017) Allostery between two binding sites in the ion channel subunit TRIP8b confers binding specificity to HCN channels. J Biol Chem 292:17718-17730
Radulovic, Jelena; Jovasevic, Vladimir; Meyer, Mariah Aa (2017) Neurobiological mechanisms of state-dependent learning. Curr Opin Neurobiol 45:92-98
Harmon, Thomas C; Magaram, Uri; McLean, David L et al. (2017) Distinct responses of Purkinje neurons and roles of simple spikes during associative motor learning in larval zebrafish. Elife 6:
Meyer, Mariah A A; Corcoran, Kevin A; Chen, Helen J et al. (2017) Neurobiological correlates of state-dependent context fear. Learn Mem 24:385-391
Han, Y; Heuermann, R J; Lyman, K A et al. (2017) HCN-channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects. Mol Psychiatry 22:458-465
Damme, Katherine S; Young, Christina B; Nusslock, Robin (2017) Elevated nucleus accumbens structural connectivity associated with proneness to hypomania: a reward hypersensitivity perspective. Soc Cogn Affect Neurosci 12:928-936
Arenas, Oscar M; Zaharieva, Emanuela E; Para, Alessia et al. (2017) Activation of planarian TRPA1 by reactive oxygen species reveals a conserved mechanism for animal nociception. Nat Neurosci 20:1686-1693
Han, Ye; Lyman, Kyle A; Clutter, Matt et al. (2016) Method for Identifying Small Molecule Inhibitors of the Protein-protein Interaction Between HCN1 and TRIP8b. J Vis Exp :

Showing the most recent 10 out of 54 publications