This is the second resubmission of a competing renewal for a neurobiology training grant now in its 26th year. The program is called BNAT, which stands for Basic Neuroscience Advanced Training. This reflects our goal to provide training for advanced pre-doctoral students and postdoctoral fellows in basic neuroscience, especially molecular, cellular, and developmental neuroscience. In the previous submission, we proposed significant new changes in the program in response to the initial review. We have begun to implement those changes. In particular, we have strengthened the administrative structure of the program, and we have created a new programmatic focus on fluorescence imaging, involving the creation of genetically-encoded fluorophores and the use of advanced fluorescence microscopes. In this revised application, we have further strengthened the BNAT administrative structure, as suggested by Reviewer 2, particularly in terms of creating a database of pre- and postdoctoral applicants. In addition, we have proactively made a major new commitment to minority training, by establishing a formal collaborative partnership with the Denver School of Science and Technology. Finally, our fifteen trainers remain very active researchers, being principal investigators on 31 extramural research grants, 17 of which are NIH R01s.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Institutional National Research Service Award (T32)
Project #
5T32NS007083-29
Application #
7841737
Study Section
NST-2 Subcommittee (NST)
Program Officer
Korn, Stephen J
Project Start
1979-07-01
Project End
2012-06-30
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
29
Fiscal Year
2010
Total Cost
$1
Indirect Cost
Name
University of Colorado Denver
Department
Physiology
Type
Schools of Medicine
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Woolfrey, Kevin M; Sanderson, Jennifer L; Dell'Acqua, Mark L (2015) The palmitoyl acyltransferase DHHC2 regulates recycling endosome exocytosis and synaptic potentiation through palmitoylation of AKAP79/150. J Neurosci 35:442-56
Stubblefield, Elizabeth A; Costabile, Jamie D; Felsen, Gidon (2013) Optogenetic investigation of the role of the superior colliculus in orienting movements. Behav Brain Res 255:55-63
Groenke, Sabine; Larson, Eric D; Alber, Sarah et al. (2013) Complete atrial-specific knockout of sodium-calcium exchange eliminates sinoatrial node pacemaker activity. PLoS One 8:e81633
Larson, Eric D; St Clair, Joshua R; Sumner, Whitney A et al. (2013) Depressed pacemaker activity of sinoatrial node myocytes contributes to the age-dependent decline in maximum heart rate. Proc Natl Acad Sci U S A 110:18011-6
Thornton, Jennifer L; Chevallier, Keely M; Koka, Kanthaiah et al. (2013) Conductive hearing loss induced by experimental middle-ear effusion in a chinchilla model reveals impaired tympanic membrane-coupled ossicular chain movement. J Assoc Res Otolaryngol 14:451-64
Al-Juboori, Saif I; Dondzillo, Anna; Stubblefield, Elizabeth A et al. (2013) Light scattering properties vary across different regions of the adult mouse brain. PLoS One 8:e67626
St Clair, Joshua R; Liao, Zhandi; Larson, Eric D et al. (2013) PKA-independent activation of I(f) by cAMP in mouse sinoatrial myocytes. Channels (Austin) 7:318-21
Whitesell, Jennifer D; Sorensen, Kyle A; Jarvie, Brooke C et al. (2013) Interglomerular lateral inhibition targeted on external tufted cells in the olfactory bulb. J Neurosci 33:1552-63
Li, Huiming; Pink, Matthew D; Murphy, Jonathan G et al. (2012) Balanced interactions of calcineurin with AKAP79 regulate Ca2+-calcineurin-NFAT signaling. Nat Struct Mol Biol 19:337-45
Thornton, Jennifer L; Chevallier, Keely M; Koka, Kanthaiah et al. (2012) The conductive hearing loss due to an experimentally induced middle ear effusion alters the interaural level and time difference cues to sound location. J Assoc Res Otolaryngol 13:641-54

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