This application is for a continuation of funding for a postdoctoral training program in Cellular Neurobiology. The goal of this program, which has been supported by NIH since 1968, is to provide postdoctoral fellows in their first 2 years after obtaining the Ph.D. with cutting-edge training in electrophysiological, optical, molecular, and/or structural techniques and their application to fundamental questions in neurobiology. Our program is currently training 33 pre-doctoral students and 49 postdoctoral fellows, of whom 4 are supported by this grant. Trainees, who typically spend a minimum of at least 2 years in the program, are selected for the program based on evidence indicating outstanding potential for a future career in research and are admitted based on prior research experience, publications, and letters of recommendation. Special efforts are in place to enhance the recruitment and retention of underrepresented minorities. In the program trainees are offered a rich selection of seminars, journal clubs, and technique workshops and are thus exposed to new techniques, findings and ideas. Outstanding research facilities and an exceptionally strong research environment are available to our trainees. Moreover, core facilities and shared resources offer our trainees access to state-or-the-art equipment in analytical biochemistry, molecular biology, electrophysiology, and microscopy. Our training faculty have strong research programs in their laboratories that are supported by both public and private funding agencies and are highly committed to both pre-doctoral and postdoctoral training.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Institutional National Research Service Award (T32)
Project #
5T32NS007101-35
Application #
8463254
Study Section
Special Emphasis Panel (ZNS1-SRB-P (47))
Program Officer
Korn, Stephen J
Project Start
1978-07-01
Project End
2014-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
35
Fiscal Year
2013
Total Cost
$79,562
Indirect Cost
$15,572
Name
University of California Los Angeles
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Haustein, Martin D; Kracun, Sebastian; Lu, Xiao-Hong et al. (2014) Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathway. Neuron 82:413-29
Babiec, Walter E; Guglietta, Ryan; Jami, Shekib A et al. (2014) Ionotropic NMDA receptor signaling is required for the induction of long-term depression in the mouse hippocampal CA1 region. J Neurosci 34:5285-90
Shigetomi, Eiji; Jackson-Weaver, Olan; Huckstepp, Robert T et al. (2013) TRPA1 channels are regulators of astrocyte basal calcium levels and long-term potentiation via constitutive D-serine release. J Neurosci 33:10143-53
Shigetomi, Eiji; Bushong, Eric A; Haustein, Martin D et al. (2013) Imaging calcium microdomains within entire astrocyte territories and endfeet with GCaMPs expressed using adeno-associated viruses. J Gen Physiol 141:633-47
Dellal, Shlomo S; Luo, Ray; Otis, Thomas S (2012) GABAA receptors increase excitability and conduction velocity of cerebellar parallel fiber axons. J Neurophysiol 107:2958-70
Issa, Fadi A; Mazzochi, Christopher; Mock, Allan F et al. (2011) Spinocerebellar ataxia type 13 mutant potassium channel alters neuronal excitability and causes locomotor deficits in zebrafish. J Neurosci 31:6831-41
Chaudhury, Dipesh; Loh, Dawn H; Dragich, Joanna M et al. (2008) Select cognitive deficits in vasoactive intestinal peptide deficient mice. BMC Neurosci 9:63
Wojtowicz, Woj M; Flanagan, John J; Millard, S Sean et al. (2004) Alternative splicing of Drosophila Dscam generates axon guidance receptors that exhibit isoform-specific homophilic binding. Cell 118:619-33
Eskandari, S; Zampighi, G A; Leung, D W et al. (2002) Inhibition of gap junction hemichannels by chloride channel blockers. J Membr Biol 185:93-102
Zampighi, G A; Eskandari, S; Kreman, M (2000) Epithelial organization of the mammalian lens. Exp Eye Res 71:415-35

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