This is a proposal to continue a long-standing postdoctoral training program at Brandeis University. This program is designed to enhance the quantitative skills of a diverse group of investigators involved in solving the problems posed by myriad disorders of the nervous system. To understand neurological disorders and develop new therapies a cadre of outstanding investigators with strong quantitative skills working in research intensive academic institutions, in industry, and in other capacities, is required. Trainees with PhDs in mathematics, physics, engineering, and computer science will be brought into neuroscience through a program of mentored laboratory research and course work. Trainees with PhDs in the biological sciences will enter a program of mentored laboratory research and receive additional training in applying quantitative methods to understand basic and translational work in neuroscience. All trainees will participate in seminars, journal clubs, and will obtain mentoring experience and training in the responsible conduct of science. Efforts to increase the diversity of the scientific work force are described.

Public Health Relevance

. Brain disorders are responsible for significant pain and suffering and economic cost. To facilitate the understanding of brain function and the development of new therapies for brain disorders, this program will produce a generation of quantitatively strong brain scientists.

National Institute of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Special Emphasis Panel (ZNS1 (56))
Program Officer
Korn, Stephen J
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Brandeis University
Schools of Arts and Sciences
United States
Zip Code
Parisky, Katherine M; Agosto Rivera, José L; Donelson, Nathan C et al. (2016) Reorganization of Sleep by Temperature in Drosophila Requires Light, the Homeostat, and the Circadian Clock. Curr Biol 26:882-92
Henty-Ridilla, Jessica L; Rankova, Aneliya; Eskin, Julian A et al. (2016) Accelerated actin filament polymerization from microtubule plus ends. Science 352:1004-9
Frey, E; Valakh, V; Karney-Grobe, S et al. (2015) An in vitro assay to study induction of the regenerative state in sensory neurons. Exp Neurol 263:350-63
Duan, Aranda R; Varela, Carmen; Zhang, Yuchun et al. (2015) Delta frequency optogenetic stimulation of the thalamic nucleus reuniens is sufficient to produce working memory deficits: relevance to schizophrenia. Biol Psychiatry 77:1098-107
O'Leary, Timothy; Sutton, Alexander C; Marder, Eve (2015) Computational models in the age of large datasets. Curr Opin Neurobiol 32:87-94
Henty-Ridilla, Jessica L; Goode, Bruce L (2015) Global resource distribution: allocation of actin building blocks by profilin. Dev Cell 32:5-6
Barbagallo, Belinda; Garrity, Paul A (2015) Temperature sensation in Drosophila. Curr Opin Neurobiol 34:8-13
Rogers, Chad S; Wingfield, Arthur (2015) Stimulus-independent semantic bias misdirects word recognition in older adults. J Acoust Soc Am 138:EL26-30
Rodal, Avital A; Del Signore, Steven J; Martin, Adam C (2015) Drosophila comes of age as a model system for understanding the function of cytoskeletal proteins in cells, tissues, and organisms. Cytoskeleton (Hoboken) 72:207-24
Neal, Scott J; Takeishi, Asuka; O'Donnell, Michael P et al. (2015) Feeding state-dependent regulation of developmental plasticity via CaMKI and neuroendocrine signaling. Elife 4:

Showing the most recent 10 out of 94 publications