The Research Training Program in Veterinary and Comparative Pathology at Harvard Medical School (HMS) is designed to prepare veterinarians for careers in biomedical research, with an emphasis on training in experimental pathology and in the use of nonhuman primate (NHP) models to study the pathogenesis and treatment of human diseases. This training grant is centered at the New England Primate Research Center (NEPRC) and includes the participation of other components of HMS and other area institutions. All trainees are at the postdoctoral level and are appointed as Research Fellows in the Department of Pathology of HMS. The training program is designed to follow a one year, NEPRC-funded period of intensive training in anatomical pathology. After appointment to the NCRR T32 program, trainees receive instruction in the design and implementation of experiments using NHP models, mentoring in the preparation of NIH grant applications and the peer review process, and broad exposure to state-of-the-art investigative tools and contemporary research methods used in experimental pathology, including immunohistochemistry, immunoelectron microscopy, in situ hybridization, flow cytometry, confocal microscopy, laser capture microdissection, PCR, and molecular biology. The training program will include formal coursework at HMS and the Harvard School of Public Health, participation in research conferences and seminars at the NEPRC, attendance at national and regional pathology and scientific meetings, and the completion of a research project under the supervision of an established investigator that results in the publication of manuscripts in peer-reviewed journals. Trainees pursuing a graduate degree may apply the research projects performed while supported by this training grant towards the fulfillment of the requirements of a PhD in graduate programs at Harvard University or the University of Massachusetts Medical School. Thus, this comprehensive training program will integrate the unique resources of the NEPRC, the outstanding research environment of Harvard Medical School and its affiliated institutions, and a field of established investigators to accomplish the long-term objective of providing qualified veterinarians with the requisite research training and experience to enable them to successfully compete for research funding as they prepare for academic careers as experimental pathologists and research scientists.
(provided by applicant): The Research Training Program in Veterinary and Comparative Pathology at Harvard Medical School is designed to provide advanced training to veterinarians for careers in biomedical research. Such individuals are valuable for their multidisciplinary skills and provide critical functions in addressing a variety of important human and animal health issues.
|Kaliyaperumal, Saravanan; WÃ¼thrich, Christian; Westmoreland, Susan V et al. (2015) Simian Virus 40 Infection in the Spinal Cord of Simian Immunodeficiency Virus-Immunosuppressed Rhesus Macaques. J Neuropathol Exp Neurol 74:1071-6|
|Schell, John B; Bahl, Kapil; Folta-Stogniew, Ewa et al. (2015) Antigenic requirement for Gag in a vaccine that protects against high-dose mucosal challenge with simian immunodeficiency virus. Virology 476:405-12|
|O'Connell, Karyn E; Guo, Wen; Serra, Carlo et al. (2015) The effects of an ActRIIb receptor Fc fusion protein ligand trap in juvenile simian immunodeficiency virus-infected rhesus macaques. FASEB J 29:1165-75|
|Assaf, B T; Knight, H L; Miller, A D (2015) rhesus cytomegalovirus (macacine herpesvirus 3)-associated facial neuritis in simian immunodeficiency virus-infected rhesus macaques (Macaca mulatta). Vet Pathol 52:217-23|
|Harbison, C E; Taheri, F; Knight, H et al. (2015) Immunohistochemical Characterization of Large Intestinal Adenocarcinoma in the Rhesus Macaque (Macaca mulatta). Vet Pathol 52:732-40|
|Abdel-Motal, U M; Harbison, C; Han, T et al. (2014) Prolonged expression of an anti-HIV-1 gp120 minibody to the female rhesus macaque lower genital tract by AAV gene transfer. Gene Ther 21:802-10|
|Petrosky, Keiko Y; Knight, Heather L; Westmoreland, Susan V et al. (2014) Atypical nodular astrocytosis in simian immunodeficiency virus-infected rhesus macaques (Macaca mulatta). J Med Primatol 43:468-76|
|Macri, S M Cummings; Masek-Hammerman, K; Crowell, A M et al. (2014) Polioencephalomalacia secondary to hypernatremia in squirrel monkeys (Saimiri sciureus). Vet Pathol 51:651-8|
|Harbison, Carole; Zhuang, Ke; Gettie, Agegnehu et al. (2014) Giant cell encephalitis and microglial infection with mucosally transmitted simian-human immunodeficiency virus SHIVSF162P3N in rhesus macaques. J Neurovirol 20:62-72|
|Gambhira, Ratish; Keele, Brandon F; Schell, John B et al. (2014) Transmitted/founder simian immunodeficiency virus envelope sequences in vesicular stomatitis and Semliki forest virus vector immunized rhesus macaques. PLoS One 9:e109678|
Showing the most recent 10 out of 23 publications