The University of California (UCD) Comparative Medical Science Training Program provides graduate research training, leading to the PhD degree, for veterinarians who seek careers in biomedical research. The training program is based in the Center for Comparative Medicine (CCM), which is a research and graduate teaching center housing faculty from the Schools of Medicine and Veterinary Medicine. CCM faculty mentors are engaged in research utilizing animal models of human disease, with major areas of emphasis in infectious disease, cancer, and genomics. Mouse biology and pathology are also major areas of emphasis, as the Center oversees the UCD Mouse Biology Program, and an NCRR Mutant Mouse Regional Resource Center. The Center interfaces with several other campus programs and centers, including the laboratory animal medicine program, the adjacent California National Primate Research Center, and residency programs in veterinary pathology and laboratory animal medicine. Students who matriculate into the program are placed with mentors within the Center, or with mentors in various affiliated programs in the School of Medicine or Veterinary Medicine, allowing customization of training emphasis to the interests of the student. The program fosters an appreciation for membership within the broad professional community of comparative medicine. The program's overall objective is to provide outstanding research training and development of skills to become competitive biomedical research scientists.

Public Health Relevance

This training program addresses the critical national shortage of research-trained veterinarians, who are needed as contributors to advancements in human biomedical research. Veterinarians contribute to biomedical research in a variety of ways, supporting animal health, as collaborating scientists, and as independent investigators. The global and comparative medical training of veterinarians, coupled with research training provided in this training program, is an ideal basis for investigation of human disease using animal model systems.

National Institute of Health (NIH)
Office of The Director, National Institutes of Health (OD)
Institutional National Research Service Award (T32)
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National Center for Research Resources Initial Review Group (RIRG)
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Moro, Manuel H
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University of California Davis
Veterinary Sciences
Schools of Veterinary Medicine
United States
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Kelly, K R; Pypendop, B H; Christe, K L (2015) Pharmacokinetics of tramadol following intravenous and oral administration in male rhesus macaques (Macaca mulatta). J Vet Pharmacol Ther 38:375-82
Lo, Michael K; Bird, Brian H; Chattopadhyay, Anasuya et al. (2014) Single-dose replication-defective VSV-based Nipah virus vaccines provide protection from lethal challenge in Syrian hamsters. Antiviral Res 101:26-9
Lopez, Christopher A; Kingsbury, Dawn D; Velazquez, Eric M et al. (2014) Collateral damage: microbiota-derived metabolites and immune function in the antibiotic era. Cell Host Microbe 16:156-63
Hodzic, Emir; Imai, Denise; Feng, Sunlian et al. (2014) Resurgence of persisting non-cultivable Borrelia burgdorferi following antibiotic treatment in mice. PLoS One 9:e86907
Spees, Alanna M; Kingsbury, Dawn D; Wangdi, Tamding et al. (2014) Neutrophils are a source of gamma interferon during acute Salmonella enterica serovar Typhimurium colitis. Infect Immun 82:1692-7
Kelly, Kristi R; Pypendop, Bruno H; Christe, Kari L (2014) Pharmacokinetics of hydromorphone after intravenous and intramuscular administration in male rhesus macaques (Macaca mulatta). J Am Assoc Lab Anim Sci 53:512-6
Kelly, K R; Pypendop, B H; Christe, K L (2014) Pharmacokinetics of buprenorphine following intravenous and intramuscular administration in male rhesus macaques (Macaca mulatta). J Vet Pharmacol Ther 37:480-5
Cissell, Derek D; Hu, Jerry C; Griffiths, Leigh G et al. (2014) Antigen removal for the production of biomechanically functional, xenogeneic tissue grafts. J Biomech 47:1987-96
Imai, Denise; Holden, Kevin; Velazquez, Eric M et al. (2013) Influence of arthritis-related protein (BBF01) on infectivity of Borrelia burgdorferi B31. BMC Microbiol 13:100
Thomasy, Sara M; Cissell, Derek D; Arzi, Boaz et al. (2013) Restrictive orbital myofibroblastic sarcoma in a cat--cross-sectional imaging (MRI & CT) appearance, treatment, and outcome. Vet Ophthalmol 16 Suppl 1:123-9

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