We are seeking to continue to expand the numbers of underrepresented minority students graduating and seeking careers in the biomedical sciences from the tenth largest producer of minority undergraduate degrees in the Nation. Over the previous four years of the MARC Grant, the numbers of minority faculty and students majoring in biology, chemistry and psychology have increased at SJSU. Our goals for the next five years are: (1) We want to raise the percentages of our MARC Trainees going on for advanced training from 75% to 90% over the five-year period of the grant. (2) We want to at least double the numbers of MARC Trainees obtaining Ph. D. or MD/Ph.D. degrees over the next grant period from 8 to at least 16 new graduates over the next 5 years. (3) We will increase the numbers of minority Ph.D.'s (who are our BA/BS students) from 2.4 to 4.8 per year for the sciences and psychology (not just MARC Trainees) through our curricula changes. (4) We want to continue working with our MARC graduates in masters programs to have at least 50% or more go on to a Ph.D. program. (5) We seek to increase the numbers of minority students remaining in science by 15% due to our curricula efforts. (6) We seek to lower the average of 6.3 years to receive a degree to 5.0 years or less for science and psychology minority students through better advising. (7) We want to increase the numbers of under-represented minority students in the sciences by 25% over five years. (8) We will make three required biology courses (BIO 1, 2, 3) more quantitative. (9) We will make two upper division biology courses more quantitative. (10) We will increase the average number of MARC publications per year from 2 to 4. The new faculty being hired are more research active and publication oriented, consistent with the higher standards for scholarship required for tenure. (11) 100% of the biology and chemistry students shall have completed calculus before becoming a MARC Trainee. These increased expectations are possible because of the curricula changes that will occur via the MARC and because the faculty are more research active.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
MARC Undergraduate NRSA Institutional Grants (T34)
Project #
Application #
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Singh, Shiva P
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
San Jose State University
Schools of Arts and Sciences
San Jose
United States
Zip Code
Tran, Alan; Tang, Angelina; O'Loughlin, Colleen T et al. (2017) C. elegans avoids toxin-producing Streptomyces using a seven transmembrane domain chemosensory receptor. Elife 6:
Ramos, Carla J; Gutierrez, Daniel A; Aranda, Ana S et al. (2016) Functional characterization of six aspartate (D) recombinant mojastin mutants (r-Moj): A second aspartate amino acid carboxyl to the RGD in r-Moj-D_ peptides is not sufficient to induce apoptosis of SK-Mel-28 cells. Toxicon 118:36-42
Gutierrez, Daniel A; Aranda, Ana S; Carrillo, David A R et al. (2016) Functional analysis of four single (RGDWL, RGDWM, RGDWP, RGDMN) and two double (RGDNM, RGDMP) mutants: The importance of methionine (M) in the functional potency of recombinant mojastin (r-Moj). Toxicon 124:1-7
Saleh, Nidal; Moore 2nd, Barry; Srebro, Monika et al. (2015) Acid/base-triggered switching of circularly polarized luminescence and electronic circular dichroism in organic and organometallic helicenes. Chemistry 21:1673-81
Shen, Chengshuo; Anger, Emmanuel; Srebro, Monika et al. (2014) Straightforward access to mono- and bis-cycloplatinated helicenes that display circularly polarized phosphorescence using crystallization resolution methods. Chem Sci 5:1915-1927
Lee, Mei-Chong W; Franco, Magdalena; Vargas, Doris M et al. (2014) A ?dinB mutation that sensitizes Escherichia coli to the lethal effects of UV- and X-radiation. Mutat Res 763-764:19-27
Franco, Joy A; Kloefkorn, Heidi E; Hochman, Shawn et al. (2014) An in vitro adult mouse muscle-nerve preparation for studying the firing properties of muscle afferents. J Vis Exp :51948
Tohgha, Urice; Deol, Kirandeep K; Porter, Ashlin G et al. (2013) Ligand induced circular dichroism and circularly polarized luminescence in CdSe quantum dots. ACS Nano 7:11094-102
Barsi-Rhyne, Benjamin J; Miller, Kristine M; Vargas, Christopher T et al. (2013) Kinesin-1 acts with netrin and DCC to maintain sensory neuron position in Caenorhabditis elegans. Genetics 194:175-87
Castellano, Brian M; Eggers, Daryl K (2013) Experimental support for a desolvation energy term in governing equations for binding equilibria. J Phys Chem B 117:8180-8

Showing the most recent 10 out of 36 publications