The major goal of this Program is to develop a new generation of physician-scientists. In order to accomplish this goal, selected medical students will gain a positive, comprehensive experience and training in biomedical research. They will (1) develop written proposals under the supervision of well-funded faculty preceptors, (2) conduct their projects in established and productive laboratories or clinical facilities for 2-3 months during option periods, usually between their first year and second years of medical school, (3) report their results in oral and written form, and (4) participate in research-related activities, i.e. seminars. These experiences will enhance their interest in and awareness of careers in academic medicine. Twenty-four training positions will be offered each year. With the guidance of faculty research mentors, students will develop 4-5 page proposals that are goal-oriented, achievable, and include a hypothesis, literature review, and methodology. Applicants will be selected by peer review based on the quality of the proposal, productivity of the mentor, and training environment. At the end of the project, a final written report is required. Other Program enhancements include a seminar series, special lectures, and opportunities to present and publish the work. Special efforts will continue to be made to attract ethnic minority individuals. A wide variety of scientific programs (basic, clinical and translational) will be considered for funding in order to accommodate a broad range of medical student interests. Research areas reflecting funding from NIDDK are somewhat prioritized. Research projects will be available in (1) Endocrinology and Metabolism, (2) Molecular Biology, (3) Physiology and Biophysics, (4) Cardiovascular Diseases, (5) Connective Tissue Diseases, (6) Infectious Disease and Immunology, (7) Cancer, (8) Neurosciences, (9) Visual System, and (10) Preventive Medicine. Seventy-two faculty members, holding over $32.5 million in annual grant awards and $33.0 million in pending grants, are currently at available at UTHSC as research preceptors. Additional faculty members who meet these high standards will be included as preceptors in the future.
The MSRF program is the entry level for medical students to explore a career in research and academic medicine. A number of students will follow through and years later become physician-scientists investigating our major diseases, including diabetes mellitus, atherosclerosis, obesity, heart disease etc. This early experience in research results in a noticeable increase in physician-scientists later, investigating mechanisms and contributing to new treatments, leading to improvements in our public health.
|Stentz, Frankie B; Brewer, Amy; Wan, Jim et al. (2016) Remission of pre-diabetes to normal glucose tolerance in obese adults with high protein versus high carbohydrate diet: randomized control trial. BMJ Open Diabetes Res Care 4:e000258|
|Chong, R William; Vasudevan, Vijaya; Zuber, Jeffrey et al. (2016) Metformin Has a Positive Therapeutic Effect on Prostate Cancer in Patients With Type 2 Diabetes Mellitus. Am J Med Sci 351:416-9|
|Kansal, Rita G; McCravy, Matthew S; Basham, Jacob H et al. (2016) Inhibition of melanocortin 1 receptor slows melanoma growth, reduces tumor heterogeneity and increases survival. Oncotarget 7:26331-45|
|Bulger, David A; Conley, Jermaine; Conner, Spencer H et al. (2015) Role of PTEN in TNFÎ± induced insulin resistance. Biochem Biophys Res Commun 461:533-6|
|Dale, James B; Niedermeyer, Shannon E; Agbaosi, Tina et al. (2015) Protective immunogenicity of group A streptococcal M-related proteins. Clin Vaccine Immunol 22:344-50|
|Levin, Michael C; Lee, Sangmin; Gardner, Lidia A et al. (2013) Autoantibodies to Non-myelin Antigens as Contributors to the Pathogenesis of Multiple Sclerosis. J Clin Cell Immunol 4:|
|Herr, Michael J; Kotha, Jayaprakash; Hagedorn, Nikolaus et al. (2013) Tetraspanin CD9 promotes the invasive phenotype of human fibrosarcoma cells via upregulation of matrix metalloproteinase-9. PLoS One 8:e67766|
|Hagopian, William; Ferry Jr, Robert J; Sherry, Nicole et al. (2013) Teplizumab preserves C-peptide in recent-onset type 1 diabetes: two-year results from the randomized, placebo-controlled ProtÃ©gÃ© trial. Diabetes 62:3901-8|
|Siddiqi, Shahzad; Sheth, Atur; Patel, Feenalie et al. (2013) Intestinal caveolin-1 is important for dietary fatty acid absorption. Biochim Biophys Acta 1831:1311-21|
|Kitabchi, Abbas E; McDaniel, Kristin A; Wan, Jim Y et al. (2013) Effects of high-protein versus high-carbohydrate diets on markers of Î²-cell function, oxidative stress, lipid peroxidation, proinflammatory cytokines, and adipokines in obese, premenopausal women without diabetes: a randomized controlled trial. Diabetes Care 36:1919-25|
Showing the most recent 10 out of 80 publications