The Alpert Medical School Summer Research Program (AMSSRP) in Molecular Pathobiology and Health Services/Outcomes research in cardiopulmonary diseases proposes to support summer research training. The primary objectives are to provide medical students with experience in biomedical research and to encourage them to embark on careers as physician scientists. A secondary objective is to provide students with a single research mentor and focus that will follow them through the entirety of their medical school training. The larger context for the AMSSRP is a unique Scholarly Concentrations (SC) program that encourages students to develop a scholarly interest that they pursue during all four years of medical school. Support is sought for 6 students to spend 10 weeks in the summer following the first year of medical school working in a research laboratory at Brown under the supervision of a faculty trainer. Twenty-six Brown researchers with extensive training experience from a variety of disciplines and departments will offer students the opportunity to join their laboratories for summer research. Seven junior faculty members will also serve as trainers. These individuals will be paired with senior faculty to provide guidance in mentoring students. Faculty will also serve as the student's Concentration mentors. Students will develop a research proposal and preliminary Concentration proposal during the winter of their first medical school year. The AMSSRP Executive Committee will evaluate the proposals and make awards based on scientific merit and the student's potential for and commitment to a research career. In addition to the mentored research experience, students will participate in weekly seminars on core research subjects, including the ethical conduct of research. Faculty trainers will participate in these seminars, both describing their research and discussing their own career development. During the fall after their summer experience, students will present their research at a medical school-wide student research symposium. The AMSSRP will provide our students with research experience that, as a component of the SC program, will serve to promote their development as physician-scientists with a focus on cardiopulmonary diseases.

Public Health Relevance

By providing students with a research opportunity early in their medical school career, and by incorporating this research experience into a broader, four-year scholarly undertaking, this project will promote the development of physician-scientists. Such individuals are the foundation for developing new approaches to health and disease and the provision of health care.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
NRSA Short -Term Research Training (T35)
Project #
Application #
Study Section
Special Emphasis Panel (ZHL1-CSR-K (O1))
Program Officer
Carlson, Drew E
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Brown University
Schools of Medicine
United States
Zip Code
Khan, Nazia; Lambert-Messerlian, Geralyn; Monteiro, Joao Filipe et al. (2018) Oxidative and carbonyl stress in pregnant women with obstructive sleep apnea. Sleep Breath 22:233-240
Sellke, Nicholas; Kuczmarski, Alex; Lawandy, Isabella et al. (2018) Enhanced coronary arteriolar contraction to vasopressin in patients with diabetes after cardiac surgery. J Thorac Cardiovasc Surg 156:2098-2107
Lauro, Peter M; Lee, Shane; Ahn, Minkyu et al. (2018) DBStar: An Open-Source Tool Kit for Imaging Analysis with Patient-Customized Deep Brain Stimulation Platforms. Stereotact Funct Neurosurg 96:13-21
Salameh, Myriam; Lee, Jennifer; Palomaki, Glenn et al. (2018) Snoring and markers of fetal and placental wellbeing. Clin Chim Acta 485:139-143
Sellke, Nicholas; Gordon, Caroline; Lawandy, Isabella et al. (2018) Impaired coronary contraction to phenylephrine after cardioplegic arrest in diabetic patients. J Surg Res 230:80-86
Soemedi, Rachel; Cygan, Kamil J; Rhine, Christy L et al. (2017) The effects of structure on pre-mRNA processing and stability. Methods 125:36-44
Lee, Jennifer; Eklund, Elizabeth E; Lambert-Messerlian, Geralyn et al. (2017) Serum Progesterone Levels in Pregnant Women with Obstructive Sleep Apnea: A Case Control Study. J Womens Health (Larchmt) 26:259-265
Feng, Jun; Anderson, Kelsey; Singh, Arun K et al. (2017) Diabetes Upregulation of Cyclooxygenase 2 Contributes to Altered Coronary Reactivity After Cardiac Surgery. Ann Thorac Surg 104:568-576
Feng, Jun; Liu, Yuhong; Singh, Arun K et al. (2017) Effects of diabetes and cardiopulmonary bypass on expression of adherens junction proteins in human peripheral tissue. Surgery 161:823-829
Uzun, Alper; Sahin, Yavuz; Schuster, Jessica S et al. (2016) Structural and genomic variation in preterm birth. Pediatr Res 80:829-836

Showing the most recent 10 out of 28 publications