There is a shortage of well-trained research-oriented pediatric pulmonologists who are prepared to develop new approaches to prevent, diagnose and treat childhood respiratory diseases. This limited pool of well- established investigators is further threatened by a decreasing number of young physician scientists who choose to specialize in pediatric pulmonary and sleep medicine. Training at all levels is an important priority at Cincinnati Children's Hospital which has established extensive programs for developing MD, PHD and MD/PhD fellows and faculty into independent clinical and basic science investigators. The Pediatric Pulmonary Division at Cincinnati Children's Hospital Medical Center (CCHMC) is uniquely positioned to interest students in both pediatric pulmonary and sleep medicine. Pulmonary research at CCHMC has very strong and diverse clinical and basic science research programs and the Sleep Disorder Center is one of the few pediatric programs in the United States that has a certified pediatric sleep fellowship program with an extensive research focus. This proposal will provide a 10 week summer research fellowship for 7 to 8 students from all US medical and osteopathic schools from which under-represented groups will be recruited. The proposed program will have a well-organized method of selection of trainees and mentors as well as an effective means of assessing the trainees'progress. A faculty of 26 MDs, PhDs and MD/PhDs from multiple departments with a proven record of success in research and mentoring are available to the trainees. All investigators are well-funded in NHLBI- focused research areas. Included within the program are opportunities to pursue basic and clinical research projects with weekly meetings at which instruction in responsible conduct of research and specific clinical and research topics in pulmonary and sleep medicine are provided. Students present their proposed projects to peers and mentors at the beginning of the summer and at the end of summer symposium when the results are presented in a poster format. The strengths of our research programs in the areas of pulmonary and sleep medicine combined with an enthusiastic faculty and a well-organized summer program provides an excellent opportunity to attract physician trainees at early and critical stages in their careers and increase the likelihood they will want to further pursue research as physician-scientists.

Public Health Relevance

There is a shortage of well-trained research-oriented pediatric pulmonologists who are prepared to develop new approaches to prevent, diagnose and treat childhood respiratory diseases. This proposal will provide a 10 week summer research fellowship for 7 to 8 students from all US medical and osteopathic schools from which under-represented groups will be recruited. The strengths of our research programs in the areas of pulmonary and sleep medicine combined with an enthusiastic faculty and a well-organized summer program provides an excellent opportunity to attract physician trainees at early and critical stages in their careers and increase the likelihood they will want to further pursue research as physician-scientists.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
NRSA Short -Term Research Training (T35)
Project #
5T35HL113229-03
Application #
8661277
Study Section
Special Emphasis Panel (ZHL1)
Program Officer
Colombini-Hatch, Sandra
Project Start
2012-05-01
Project End
2016-04-30
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
3
Fiscal Year
2014
Total Cost
Indirect Cost
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Cleveland, Zackary I; Zhou, Yu M; Akinyi, Teckla G et al. (2017) Magnetic resonance imaging of disease progression and resolution in a transgenic mouse model of pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol 312:L488-L499
Zhang, Zhonghua; Biagini Myers, Jocelyn M; Brandt, Eric B et al. (2017) ?-Glucan exacerbates allergic asthma independent of fungal sensitization and promotes steroid-resistant TH2/TH17 responses. J Allergy Clin Immunol 139:54-65.e8
Arora, Kavisha; Yarlagadda, Sunitha; Zhang, Weiqiang et al. (2016) Personalized medicine in cystic fibrosis: genistein supplementation as a treatment option for patients with a rare S1045Y-CFTR mutation. Am J Physiol Lung Cell Mol Physiol 311:L364-74
Florin, Todd A; Carron, Hannah; Huang, Guixia et al. (2016) Pneumonia in Children Presenting to the Emergency Department With an Asthma Exacerbation. JAMA Pediatr 170:803-5
Roach, David J; Crémillieux, Yannick; Fleck, Robert J et al. (2016) Ultrashort Echo-Time Magnetic Resonance Imaging Is a Sensitive Method for the Evaluation of Early Cystic Fibrosis Lung Disease. Ann Am Thorac Soc 13:1923-1931
Cheng, Joy; Purcell, Hillary N; Dimitriou, Sophia M et al. (2015) Testing the feasibility and acceptability of a chaplaincy intervention to improving treatment attitudes and self-efficacy of adolescents with cystic fibrosis: a pilot study. J Health Care Chaplain 21:76-90
Beebe, Dean W; Zhou, Amy; Rausch, Joseph et al. (2015) The Impact of Early Bedtimes on Adolescent Caloric Intake Varies by Chronotype. J Adolesc Health 57:120-2
Purcell, Hillary N; Whisenhunt, Allison; Cheng, Joy et al. (2015) ""A remarkable experience of god, shaping us as a family"": parents' use of faith following child's rare disease diagnosis. J Health Care Chaplain 21:25-38
Sun, Hongtao; Harris, William T; Kortyka, Stephanie et al. (2014) Tgf-beta downregulation of distinct chloride channels in cystic fibrosis-affected epithelia. PLoS One 9:e106842