Establishing the University of Illinois at Chicago (UlC) Center for Clinical and Translational Science (CCTS) will fundamentally alter the nature of clinical and translational Investigation at UlC and our partners (Advocate Health Care, Jesse Brown VA Medical Center, Ul Peoria, Ul Rockford, Ul Urbana). Harnessing our diversity of background, interests and expertise, the UlC CCTS will effectively catalyze collaborative thinking and innovation. The CCTS will organize, finance, and house the infrastructure, expertise, and resources of value to clinical translational investigators within a single academic home, with leadership that reports to the highest levels of UlC administration. This reorganization crosses administrative boundaries to harness and enhance existing UlC resources. A major element of UlC's vision for its future its operationalized by establishing the UlC CCTS, which will have the following Specific Aims.
Specific Aim # 1: Create and develop an academic home for clinical translational research at UlC. This home will provide a flexible and adaptable infrastructure to stimulate collaborative thinking, generative discourse, and collective action to facilitate clinical and translational investigation. The creation of this home will include establishing a robust Pilot Grant Program, a Clinical and Translational Science Academy, a web-based and geographic slngle-point-of-access for investigators to make use of CCTS expertise and resources, and a CCTS Matchmaking service to identify and catalyze novel collaborations.
Specific Aim # 2 contributes to the academic home by establishing the research service infrastructure (the 6 Research Service Cores) to provide clinical research support services required by clinical and translational investigators.
Specific Aim # 3 contributes to creation of the academic home by providing multifaceted educational experiences for pre-and post-doctoral trainees, junior faculty, and established faculty wishing to extend their thinking beyond their current disciplinary boundaries. Establishing the UlC CCTS will optimize collaboration with our key clinical research partners, and allow us to facilitate new and innovative investigation in pediatrics and community-based science. The administrative reorganization represented by the UlC CCTS will lead to rationalization and integration of significant and mature UlC resources for clinical translational research. It will add to these resources to produce something better for clinical translational researchers and trainees at UlC and at key partner institutions. PERFORMANCE SITE(S) (organization, city, state) University of Illinois at Chicago, Chicago, IL Advocate Health Care, Oakbrook, IL Jesse Brown VA Medical Center, Chicago, IL University of Illinois, Peoria, IL University of Illinois, Rockford, IL University of Illinois, Urbana, IL PHS 398 (Rev, 11/07) Page 2 Form Page 2

Agency
National Institute of Health (NIH)
Institute
National Center for Advancing Translational Sciences (NCATS)
Type
Linked Training Award (TL1)
Project #
3TL1TR000049-05S1
Application #
8846200
Study Section
Special Emphasis Panel (ZRR1)
Program Officer
Wilde, David B
Project Start
2009-07-14
Project End
2015-03-31
Budget Start
2014-05-15
Budget End
2015-03-31
Support Year
5
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
City
Chicago
State
IL
Country
United States
Zip Code
60612
Farabi, Sarah S; Carley, David W; Quinn, Lauretta (2017) Glucose Variations and Activity Are Strongly Coupled in Sleep and Wake in Young Adults With Type 1 Diabetes. Biol Res Nurs 19:249-257
Meerschaert, Mark M; Magin, Richard L; Ye, Allen Q (2016) Anisotropic fractional diffusion tensor imaging. J Vib Control 22:2211-2221
Berth, Sarah H; Mesnard-Hoaglin, Nichole; Wang, Bin et al. (2016) HIV Glycoprotein Gp120 Impairs Fast Axonal Transport by Activating Tak1 Signaling Pathways. ASN Neuro 8:
Berth, Sarah; Caicedo, Hector Hugo; Sarma, Tulika et al. (2015) Internalization and axonal transport of the HIV glycoprotein gp120. ASN Neuro 7:
Ye, Allen Q; Zhan, Liang; Conrin, Sean et al. (2015) Measuring embeddedness: Hierarchical scale-dependent information exchange efficiency of the human brain connectome. Hum Brain Mapp 36:3653-65
Gatto, Rodolfo G; Chu, Yaping; Ye, Allen Q et al. (2015) Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease. Hum Mol Genet 24:5285-98
Cone, Jackson J; Roitman, Jamie D; Roitman, Mitchell F (2015) Ghrelin regulates phasic dopamine and nucleus accumbens signaling evoked by food-predictive stimuli. J Neurochem 133:844-56
Nemanich, Samuel T; Earhart, Gammon M (2015) How do age and nature of the motor task influence visuomotor adaptation? Gait Posture 42:564-8
Ye, Allen Q; Ajilore, Olusola A; Conte, Giorgio et al. (2015) The intrinsic geometry of the human brain connectome. Brain Inform 2:197-210
Ye, Allen Q; Hubbard Cristinacce, Penny L; Zhou, Feng-Lei et al. (2014) Diffusion tensor MRI phantom exhibits anomalous diffusion. Conf Proc IEEE Eng Med Biol Soc 2014:746-9

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